Sulfadiazine Flashcards
Sulfadiazine
Antibiotic
Sulfadiazine Action
inhibit bacterial growth by preventing the synthesis of a folic acid derivative
Folic acid is essential for the production of DNA, RNA, and proteins.
Sulfadiazine Use
It is used to treat many different kinds of bacterial infections, like those of the brain, ears, and urinary tract.
It is also used to prevent infections in people who are at risk.
It will not work for colds, flu, or other viral infections.
Sulfadiazine Complication
Hypersensitivity
Blood dyscrasias
Crystalluria
Kernicterus
Hyperkalemia
Sulfadiazine Contrainidications
Warnings
Pregnancy/Lactation
Use cautiously in clients who have impaired kidney function (give lower dosages).
Administer with caution to adults older than 65 years who take ACE inhibitors or angiotensin II receptor blockers because of the risk for hyperkalemia.
Sulfadiazine Interactions
Increased effects of warfarin, phenytoin, sulfonylurea oral hypoglycemics
Sulfadiazine Education
Complete the entire course of therapy, even if manifestations resolve sooner.
Sulfadiazine Dose
25 to 50 mg/kg (maximum 1 to 1.5 g/dose)