Baclofen

Question 1

Baclofen

Answer 1

Muscle Relaxant

Antispasmodics

Question 2

Baclofen Action

Answer 2

Acts in the CNS to enhance GABA, produce sedative effects, and depress hyperactive spasticity of muscles. There are no direct effects on skeletal muscles.

Question 3

Baclofen Use

Answer 3

Relief of spasticity related to cerebral palsy, spinal cord injury, and multiple sclerosis

Question 4

Baclofen Complications

Answer 4

Nausea, constipation, urinary retention, seizures

Question 5

Baclofen Contrainidications

Answer 5

Safety not established for pregnancy or lactation

Hypersensitive

Question 6

Baclofen Interations

Answer 6

CNS depressants (alcohol, opioids, antihistamines) have additive CNS depressant effects, and can cause severe respiratory depression

Question 7

Baclofen Education

Answer 7

Monitor for adverse effects and notify the provider if they occur.

Take with meals to reduce gastric upset.

Increase intake of high-fiber foods.

Avoid driving

Question 8

Baclofen Dose

Answer 8

5mg/tid (Initial)