Suffolk Final Flashcards
Medical science that deals with functioning and disorders of the nervous system
Nuerology
The nervous system is responsible for all
Behaviors memories and movements
Three basic functions of the nervous system
Sensory
Interpretation
Motor response
Sensing changes with sensory receptors, detects internal and external environment
Sensory receptors
Analysis, interpreting and remembering changes with the sensory receptors
Interpretation
Reaction to changes with effectors
Motor response
Nervous system path overview
Receptor Sensory neuron Inter neuron Motor neuron Muscle
The brain and the spinal cord are part of the
Central nervous system
CNS
The cranial nerves
Spinal nerves
Ganglia
Peripheral nerves are all part of the
Peripheral nervous system
A bundle of hundreds or thousands of axons each of which courses along a defined path and serves a specific region of the body
Nerve
Located outside the brain and spinal cord are small masses of nervous tissue containing cell bodies of nuerons
Ganglia
Helps regulate the digestive system
Plexuses
Parts if neurons or specialized cells that minister changes in the external or internal environment
Sensory receptors
Neurons from cutaneous and special sensory receptors to the CNS
Motor neurons to skeletal muscle tissue
Somatic voluntary nervous system SNS
Sensory neurons from visceral organs to CNS
Motor neurons to smooth and cardiac muscle & glands
Autonomic involuntary nervous system
Sympathetic division of the autonomic nervous system
Speeds up heart rate
Parasympathetic division of the autonomic nervous system
Slows down heart rate
Involuntary sensory & motor neurons control GI tract
Neurons function independently of ANS and SNS
Enteric nervous system ENS
Consists of neurons in the plexusus that extend the length of GI tract
Enteric nervous system ENS
Sensory neurons of the ENS moniter chemical changes within the GI tract and stretching of its walls
.
Somatic nervous system pathway
SNS
CNS
Somatic motor nuerons
Skeletal muscle
ANS autonomic nervous system pathway
ANS
CNS
autonomic neurons sympathetic or parasympathetic
Smooth muscle, cardiac muscle and glands
ENS enteric nervous system path
ENS
CNS
enteric motor neurons in enteric plexusus
Smooth muscles, glands, cells of GI tract
What is the functional unit of the nervous system
Neurons
Glue that supports and maintains the neuronal networks and also outnumber neurons
Neuroglia
Cytoplasm of the neuron is called
Perikaryon
Mitochondria produces
Energy
RER in ribosomes in the neuron produce
Neurotransmitters
Cytoskeleton of a neuron consist of
Neurofilaments
Neurotubules
Neurofibrils
Bundles of neurofilaments that provide support for dendrites and axon
Neurofibrils
Makes neural tissue appear grAy
dense area of RER and ribosomes
Nissl bodies
Axon structure is critical to
Function
Cytoplasm of axon that contains neurotubules neurofibrils and enzymes
axoplasm
Covers the axoplasm
Axolemma
Junction in between the axon hillock and initial segment
Trigger zone
Types of neurons found in the brain and sense organs
All cell processes look alike
Anaxonic neurons
Found in special sensory organs
Sight smell hearing
Bipolar neurons
Found in sensory neurons of PNS
Fused dendrites and a very long axon
Unipolar neurons
Common in the CNS
Include all skeletal muscle motor neurons
Long axons
Multipolar neurons
Convey action potentials into the CNS through cranial or spinal nerves
Mostly unipolar
Sensory or afferent neurons
Conveys action potentials away from the CNS to effectors (muscles or glands) in the peripheral through cranial or spinal nerves
Most are multipolar
Motor or efferent neurons
Multipolar in structure
Integrates incoming sensory from sensory neurons and then Olicits a motor response
Interneurons
90% of neurons in the body are
Interneurons
4 cell types in the CNS
Astrocytes
Oligodendrocytes
Microglia
Ependymal
2 cells in the PNS
Schwann cells
Satellite cells
Does not generate or conduct nerve impulses
Neuroglia
Neuroglia supports in
Blood brain barrier
Myelin sheath ( nerve insulation)
CSF
phagocytosis
In the CNS this cell supports neurons by maintaining chemical balance of calcium and potassium
Astrocytes
In the CNS this cell produces myelin
Oligodendrocytes
In the CNS this cell conducts in phagocytosis
Microglia
In the CNS this cell forms an circulates CSF
Ependymal cells
In the PNS this cell supports the interneuron
Satellite cell
In the PNS this cell produces the myelin sheath on the interneuron
Schwann cell
this cell in the CNS helps form scar tissue after injury
Astrocytes
This cell in the CNS helps metabolize neurotransmitters
Astrocytes
Most common glial cell type found in the CNS
Oligodendrocytes
Electrically insulates the Axon and increases the speed of nerve impulse conduction
Myelin sheath
These cells wrap around Axons during fetal development
Schwann cells
White matter
Myelinated processes
Unmyelinated processes are in
Gray matter
Impulses that travel long distances
Action potential s
Impulses that are local membrane changes
Graded potentials
These channels open in the presence of specific chemicals
Ex: acetylcholine
Chemically gated channels
Change in membrane potential opens this channel
Voltage gated channel
Mechanical stimulus opens this channel
Mechanical gated channels
At resting membrane potential
A cell is polarized when negative ions are inside the cell and positive ions along outside leaving energy difference at
-70 Mv
For every 3 NA+
2 K+
When an action potential that decrease and eventually reverse the membrane potential
Depolarization
Restores membrane to its resting state
Re polarization
A stronger stimulus will not cause a larger impulse once it reaches threshold
.
If a stimulus strength is at the subthreshold there is no
No impulse will result
The threshold I’m millivolts
-55 Mv
Period of time In which a neuron cannot generAte a new action potential
Refractory period
A suprathreahold stimulus will be able to start an AP
Relative refractory period
These two local anesthetics prevent opening of voltage gated sodium channels
Novocaine
Lidocaine
Step by step depolarization of each portion of the length of the axolemma
Continuous conduction
Unmyelinated fibers
Depolarization only at nodes of ranvier
Saltatory conduction
Myelinated fibers
Factors that effect speed of propagation
Axon diameter
Temperature
Amount of myelination
Information transfer from pre synaptic to post synaptic neuron is
Chemical
Axodendritic
Axon to dendrite
Axosomatic
Axon to cell body
Axoaxonic
Axon to axon
Anything that enhances a transmitters effects
Agonist
Anything that blocks a neurotransmitters effects
Antagonist
Autoimmune disorder causing destruction of myelin sheaths in CNS
Multiple sclerosis
Where is CSF
Subarachnoid space of the spinal cord