Substances Flashcards

1
Q

Use of a single joint can lead to a positive urine marijuana test as many as this number of
days later

A

4 days later

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2
Q

Use of marijuana at an early age may interact with those who have the genetic predisposition & promote the development of this serious mental illness

A

Schizophrenia

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3
Q

The most common psychiatric adverse side effects of marijuana use is psychosis and this

A

anxiety/panic attacks

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4
Q

Cognitive effects of marijuana include amotivation, disorientation, unsteady coordination, altered perception, decreased consciousness and this reason for poor academic performance

A

memory loss

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5
Q

What percent of users become dependent on marijuana?

A

10%

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6
Q

This synthetic Cannabinoid agonist is used to treat anorexia and weight loss in AIDS patients & nausea/vomiting in patients
getting chemo

A

dronabinol (marinol)

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7
Q

Marijuana’s clinical properties include these 3 effects:

A

anti-inflammatory effects
anti-convulsant effects
anti-emetic effects

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8
Q

Which of the following most commonly describes withdrawal from marijuana:

Potentially life threatening,
Significant discomfort, or
Mild symptoms

A

Mild symptoms

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9
Q

What terms describe marijuana use that leads to a reduction in prosocial goal-directed activities that may contribute to poor school or job performance?

A

amotivational syndrome

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10
Q

This non-nicotine agent is thought to increase dopamine and norepinephrine levels and mimic some of the effects of nicotine

A

Bupropion (Wellbutrin)

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11
Q

This smoking cessation medication is a long acting partial agonist
at the α4β2NAR

A

varenicline (chantix)

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12
Q

This tricyclic antidepressant is not first-line but a second line smoking cessation agent due to its side effect profile

A

nortriptyline

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13
Q

It is unusual to rare for an individual to start smoking

after this age

A

21 years old

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14
Q

Nicotine withdrawal from smoking cessation usually begins within 24 hours, and peaks at what time post-cessation?

A

Day 2-3

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15
Q

Nicotine withdrawal from smoking cessation usually will lasts how long?

A

2-3 weeks

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16
Q

This alpha-2 adrenergic agonist is used for treating hypertension but has shown promise for smoking cessation

A

clonidine

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17
Q

What is most common tobacco use product?

A

Cigarettes

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18
Q

Disappearance of nausea and dizziness despite repeated tobacco use is an indication of this

A

Tolerance

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19
Q

For ♀ & older adults, a social or moderate drinker is one who does not binge drink & consumes on average no more than how many drinks per day?

A

One

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20
Q

This type of peptide mediates some of alcohol’s rewarding effects by enhancing the midbrain release of dopamine

A

Opioid

21
Q

This medication inhibits aldehyde dehydrogenase leading to a build up of acetaldehyde and negative reinforcement of alcohol use

A

disulfiram (antabuse)

22
Q

This medication is used in the treatment of alcohol dependence and is available in a monthly depot injection.

A

naltrexone (vivitrol)

23
Q

These two medications for alcohol use disorder are contraindicated in pts with significantly compromised
liver function.

A

disulfiram (anatbuse) and naltrexone (vivitrol)

24
Q

For ♂ who are < 65 y/o, a social or moderate drinker is one who does not binge drink & on average consumes no more than how many drinks per day?

A

Two

25
Q

This alcohol use disorder medication is an opioid mu receptor antagonist as a
treatment option

A

naltrexone (vivitrol)

26
Q

This medication helps prevent relapse, has a common side effect of diarrhea, is safe in hepatic compromised pts, but is contraindicated in pts with severe renal disease

A

acamprosate (campral)

27
Q

Naltrexone is most effective in treating this aspect of alcohol dependence

A

cravings

28
Q

Standard drug screens do not detect these drugs and usage typically declines dramatically after the teen years

A

inhalants

29
Q

The phenylalkylamines class of hallucinogens includes mescaline, DOM, and this most well known drug

A

MDMA (ecstasy, XTC)

30
Q

First developed as a anesthetic, this drug produces feelings of separation from mind and body-dissociation

A

Phencylcidine (PCP)

31
Q

Continued use of which hallucinogen has been linked to neurotoxic effects:

MDMA, LSD, or PCP

A

MDMA (ecstasy)

32
Q

Any inhaled volatile hydrocarbons (glues, fuels, paints) may produce “sudden sniffing death” due to what effect?

A

cardiac arrhythmia

33
Q

Phencylclidine (PCP) can be detected in the urine up to this many days after use

A

8 days

34
Q

The ergoline class of hallucinogens includes this drug which often produces visual hallucinations which can be frightening to the user

A

lysergic acid diethylamide (LSD)

35
Q

While lab testing can detect PCP, may or may not be helpful detecting hallucinogens, lab testing is not helpful detecting this

A

inhalants

36
Q

Intoxication with this drug may produce vertical or horizontal nystagmus, diminished responsiveness to pain, and violent behavior

A

Phencyclidine (PCP)

37
Q

The proportion of users of this are most likely to become dependent on the substance

A

nicotine

38
Q

Use of this illicit drug is most commonly involved in ER visits

A

cocaine

39
Q

When sober, users of this drug(s) may re-experience geometric visual hallucinations, flashes of color, intensified colors, or misperception of objects being too large or too small

A

hallucinogens (Primarily LSD)

40
Q

About 50% of people who attempt to quit smoking develop withdrawal and commonly complain of irritability, difficulty
concentrating, and this

A

anxiety

41
Q

About 50% of people who attempt to quit smoking develop withdrawal and commonly complain of what symptoms?

A

irritability, difficulty

concentrating, and anxiety

42
Q

Over 80% of tobacco users attempt to quit, 60% relapse within 1 week, and this proportion succeed and do not ever relapse

A

1 in 20 (5%)

43
Q

A drink is defined as a 1.5 ounce shot, this 4-6 ounces of wine, or this many ounces of beer

A

12 ounces

44
Q

A drink is defined as a 12 ounce beer, 4-6 ounces of wine, or this many ounces of a shot

A

1.5 ounce shot

45
Q

A drink is defined as a 1.5 ounce shot, a 12 ounce beer, or this many ounces of wine

A

4-6 ounces

46
Q

Psychostimulants specifically worsen these symptoms of schizophrenia

A

hallucinations and paranoia

47
Q

Use of marijuana, alcohol, or this before age 15 are considered to be the three “Gateway Drugs” to later dependence problems

A

Nicotine

48
Q

What are the three “Gateway Drugs” to later dependence problems

A

Nicotine
Marijuana
Alcohol

49
Q

What is the most common illicit drug used worldwide across all age groups?

A

Marijuana