Substance DSMV Flashcards

1
Q

Opioids can be detected through a urine drug test for this many hours after administration of the opioid

A

12-36 hours

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2
Q

This type of liver disease may occur in up to 90% of persons who inject opioids

A

hepatitis C

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3
Q

HIV, hepatitis, tuberculosis, and this cardiac related condition are serious medical problems for IV opiate users

A

bacterial endocarditis

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4
Q

This physical sign of opiate withdrawal is also “seen” in hallucinogen intoxication and stimulant intoxication

A

pupil dilation

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5
Q

Opioid intoxication may be diagnosed by administering this opioid antagonist challenge

A

naloxone (narcan)

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6
Q

These two symptoms are associated with more severe opiate withdrawal and are often not seen in routine clinical practice

A

piloerection & fever

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7
Q

Suboxone is a combination of these two medications

A

naloxone (narcan) & buprenorphine

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8
Q

What are the signs of opiate withdrawal?

A

Withdrawal: dysphoria, N/V, muscle aches, lacrimation/ rhinorrhea, pupil dilation, piloerection, fever, sweating

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9
Q

What are the signs of opioid intoxication?

A

pupil constriction, drowsiness/ coma, impaired attention or memory, slurred speech

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10
Q

Signs of opioid intoxication are pupil constriction, drowsiness/coma, impaired attention or memory,
and this

A

slurred speech

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11
Q

This can differentiate PCP intoxication & stimulant intoxication from each other

A

A urine drug test

The clinical picture is similar though rotary nystagmus may be seen in PCP intoxication but not stimulant intoxication

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12
Q

Cocaine users often use sedative substances–most often this substance–to reduce insomnia, nervousness, and other unpleasant side effects

A

Alcohol

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13
Q

Amphetamine type stimulant users often use sedative substances–most often this substance–to reduce insomnia, nervousness, and other unpleasant side effects

A

marijuana

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14
Q

This sign is often present and is a reliable measure of stimulant withdrawal

A

bradycardia

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15
Q

Bipolar disorder, schizophrenia, other substance use disorders, and this personality disorder in particular are risk factors for stimulant use disorder

A

antisocial personality disorder

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16
Q

This type of sample can be used to detect use of a stimulant up to
90 days after the use

A

A hair sample

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17
Q

These two forms of cocaine administration have the most rapid onset of action

A

inhalation and injection

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18
Q

A speedball is the combination of cocaine and this drug

A

heroin

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19
Q

Cocaine increases the levels of glutamate and this neurotransmitter

A

dopamine

20
Q

In terms of operant conditioning, the alcohol induced buzz/high is this; also tolerance results in the
lack of this

A

positive reinforcement

21
Q

In terms of operant conditioning, consuming alcohol to stave off alcohol withdrawal symptoms results in this

A

negative reinforcement

22
Q

Most substance induced disorders resolve within this amount of time after the cessation of acute withdrawal, the cessation of severe intoxication, or the use of the substance

A

1 month

Most improve within days to weeks of abstinence

23
Q

The prevalence of alcohol use disorder in this sex is twice as much as the other

A

males

Males ~12%, Females ~5%

24
Q

For an individual who has a close relative (parent) with an alcohol use disorder, their risk is this many times higher than normal

A

3-4 times

25
Q

Alcohol metabolizing enzyme genetic polymorphisms result in flushing, palpitations, & possibly more severe reactions in individuals of this race when they consume alcohol

A

Asians

Japanese, Chinese, and Koreans are at lower risk for Alcohol Use Disorders

26
Q

Elevations in these two lab test results are sensitive indicators of ongoing heavy drinking and can be used to monitor abstinence

A

gamma-glutamyltransferase (GGT) and carbohydrate-deficient transferrin (CDT)

27
Q

While elevation of GGT, CDT, and this test indicates a history of heavy drinking, GGT & CDT test may also be useful in detecting a relapse
to heavy drinking, but
this test is not

A

mean corpuscular volume (MCV)

Not useful for monitoring due to long half life of RBC’s

28
Q

The patients with bipolar disorder, schizophrenia, & this personality disorder have a markedly high rate of co-morbid alcohol use disorder

A

Antisocial Personality Disorder

29
Q

Substance use disorder pts, especially those with severe disorder, have an underlying change in this which persists even beyond detoxification

A

brain circuitry

30
Q

Continued substance use despite persistent or recurring interpersonal problems is referred to as this:

A

social impairment

31
Q

A desire to cut down or unsuccessful attempts decrease or stop use refers to this Criterion A

A

impaired control

32
Q

Pharmacological criteria refers to “putting up” with these two phenomenon

A

tolerance & withdrawal

33
Q

Taking the substance in larger amounts or over a longer time period than intended refers to this Criterion A

A

impaired control

34
Q

Use in physically hazardous situations or continued use despite knowledge the substance is causing or worsening a medical problem is called this

A

risky use

35
Q

Spending a great deal of time obtaining, using, or recovering from the substance use refers to this Criterion A

A

impaired control

36
Q

Failure to fulfill major obligations at work, home, or school refers to this Criterion A

A

social impairment

37
Q

Craving refers to this Criterion A

A

impaired control

38
Q

Caffeine intoxication may induce a sleep disorder or this type of substance induced disorder

A

anxiety

39
Q

Marijuana intoxication may induce anxiety disorders, sleep disorders, and this type of substance induced disorder

A

Psychotic disorder

40
Q

The hallucinogen phencyclidine

may induce psychotic disorders, anxiety disorders, delirium, & this type of substance induced disorders

A

mood disorders

both bipolar & depressive

41
Q

Opioid intoxication may induce sleep disorders, sexual dysfunction, delirium, & this type of substance induced disorder

A

depressive disorders

42
Q

Opioid intoxication will not, but opioid withdrawal may induce this type of substance disorder

A

anxiety

43
Q

Alcohol & sedative/hypnotic intoxication may both induce the same type of substance disorders except sedative/hypnotic
intoxication will NOT
induce this

A

anxiety

44
Q

Alcohol & sedative/hypnotic intoxication may both induce the same type of substance disorders, including:

A

Psychotic, Bipolar, Depressive, Sleep, Sexual Dysfunction, Delirium, Neurocognitive disorders

45
Q

Intoxication, but not withdrawal,

of stimulants such as cocaine may induce sexual dysfunction, delirium & this type of substance induced disorder

A

Psychotic disorders

46
Q

Intoxication & withdrawal of stimulants such as cocaine may induce, anxiety, OCD, sleep, & this type of substance induced disorder

A

mood disorders

both bipolar & depressive

47
Q

Inhalants and this type of substance do not cause a withdrawal

A

hallucinogens