Substance Misuse Flashcards
How do you support alcohol withdrawal?
You give a decreasing benzo regime Nutritional support disuphuram (hangover) acamprosate (reduces cravings) naltroxone (reduces pleasure)
What is delirium tremens?
A hyperadrenergic state, 2 days after withdrawal
An emergency in alcohol withdrawal where the patient reacts badly
Most due to stopping cold turkey too quickly
Can be fatal (30% mortality)
How common is DTs?
5% of withdrawals
What are the symptoms of DTs?
Gross Tremor Sweating (ANS arousal) Agitation and Confusion Headache Convulsions (loss of GABA inhibition) Hallucinations (tactile, visual)
Hypoglycaemia
How do you treat DTs?
Anti-convulsants Decreasing Benzo regime Anti-emetic Monitor Fluids and electrolytes Prevent hypoglycaemia
Long term help for alcohol withdrawal?
Group Therapy/AA
Acamprosate (decrease cravings)
Disuphuram (gives bad hangover symptoms due to aldehyde dehydrogenase inhibition)
Support
Nutritional support - B12, folate, thiamine (pabrinex)
Diet - encourage healthy eating
What are the symptoms of dependence?
HINT: Has an acronym
Compulsion to take
Aware of risks but cannot help it
Neglecting other activities
Time preoccupied by it
Symptoms if stop
Tolerance
Out of control
Persistant wish to cut down
What does alcohol do to the body?
Alcoholic gastritis (snake skin appearance)
GORD
Varices
Liver disease
Erectile dysfunction and infertility (virilisation)
Malignancy
Brain - encephalopathy, Korsakoffs
Pancreatitis - acute and chronic
Foetal Alcohol Syndrome
Injuries whilst intoxicated
Psychosocial - job, psychosis, depression, social life, criminal
What substances are people often addicted to?
Opioids - heroin, morphine
Benzodiazapines -
Alcohol (6% men, 2% women)
How do you treat a Benzo overdose?
Flumazanil
How do you treat a heroin (opioid) overdose?
Naloxone
What substances are depressants “downers”
Opioids
Benzos
Glue/solvents
Which drugs are psychotrophic?
Cannabis
Ecstasy
LSD
Which drugs are stimulants?
Cocaine
Amphetamines
Which substances are less addictive?
Cannabis
Solvents