Medications

Question 1

What are some SSRIs?

Answer 1

Sertraline
Fluoxetine
Citalopram

Question 2

What are some side effects of SSRIs?

Answer 2

Headache
Nausea
Increased motivation (for suicide)
Weight Gain
Agitation
Anorexia

Question 3

What are some SNRIs?

What are some side effects of SNRIs

Answer 3

Venlafaxine, Duloxetine
More severe side effects than SSRIs
Weight gain
Low Na+, high BP

Question 4

What are some TCAs
What are some side effects of TCAs
What are they also used for?

Answer 4

Amytriptiline

Turned Off
Constipation
ANS effects - sweating, nausea, diarrhoea, anxiety

Neuropathic Pain

Question 5

What is the standard dosage of SSRIs?

Answer 5

50mg Sertraline for depression (can go up to 100mg)

If anxiety/panic disorder then can give a high dose`

Question 6

What are some NARIs?

What are some side effects of NARIs?

Answer 6

Reboxetine

Feel like i’m in a box) Sweating, Tachycardia, Constipation etc (ANS

Question 7

What are some NaSSAs?

What are some side effects of NaSSa?

Answer 7

Mirtazapine
Weight Gain and increased appetite
Confusion
Tired

Question 8

What is a specific risk of Citalopram?

Answer 8

Long QTc and hypokalaemia

Question 9

How long do you take an anti-depressant for?

Answer 9

6 months after 1st episode goes

up to 2 years after second + episode

Question 10

How long does it take SSRIs to start working

Answer 10

4-6 weeks

Question 11

What is the 1st mood stabilizer?

What are some side effects of this mood stabilizers?

Answer 11

Lithium Carbonate

Leukocytosis
Increased Thirst and urine
Tremor (fine)
HypoThyroid 
Increased weight
Underactive Memory
Mothers (teratogenic)

Question 12

What are some atypical anti-psychotics?

What are some typical anti-psychotics?

Answer 12

Rispiridone
Olanzapine

Haloperidole
Chlorpromazine

Question 13

Why do you use atypical anti-psychotics more than typical?

Answer 13

As they have fewer EPSEs

Question 14

What are some side effects of anti-psychotics?

Answer 14

Increased prolactin - erectile dysfunction, dysmenorrhoea, gynaecomastia
Tremor and Parkinsonism
Sedation
Nausea
Headaches
Weight Gain and glucose tolerence

Question 15

What is the ADHD medication?

Side effects?

Answer 15

Ritalin
(Mehtyphenidate)

Growth restiction
BP raised
Seizures
Nausea and Headaches

Question 16

When do you NOT use an AChE inhibitor?

Answer 16

COPD

Question 17

What are some Alzheimers treatments?

Side effects?

Answer 17

Galantamine
Donepazil
Memantine

Bradycardia
Nausea
Syncope
AV Block

Question 18

What anti-convulsants do you use in Bipolar?

Side effects?

Answer 18

Carbamezapine
Lamotrigine

Nausea
Sedation
HypoNa+

Question 19

What is the 2nd line mood stabiliser

Answer 19

So

Question 20

What is the 2nd line mood stabiliser

Answer 20

Sodium Valproate

Ataxia
Liver Failure
Pancreatitis
Reversible Hair Loss
Oedema
Appetite Gain
Teratogenic/Tremor
Encephalopaty

Question 21

What is the 2nd line mood stabiliser

Answer 21

Sodium Valproate

Ataxia
Liver Failure
Pancreatitis
Reversible Hair Loss
Oedema
Appetite Gain
Teratogenic/Tremor
Encephalopathy

Question 22

What is the abnormality with foetuses with Lithium?

Answer 22

Ebsteins Anomaly

Question 23

What is the abnormality with foetuses with Valproate?

Answer 23

Neural tube defects

Question 24

What do you use in refractory schizophrenia?

Answer 24

Clozapine

Question 25

What are the side effects of Clozapine?

Answer 25

``` Weight Gain Agranulocytosis Increased Salivation Seizures Nausea ``` Can only do as an inpatient

Question 26

What are the EPSEs and when do they come in?

Answer 26

Dystonia (days) Akanthisia (weeks) Parkinsonism Tardive dyskinesia (months - years and are irreversible)

Question 27

What is Tardive dyskinesia?

Answer 27

Involuntary, stiff, jerky, repetitive movements Tongue sticking out, lip smacking

Question 28

What is dystonia?

Answer 28

Painful, involuntary muscle spasms e.g. torticollis

Question 29

What is neuroleptic malignant syndrome?

Answer 29

``` Severe reaction to an anti-psychotic --> ICU You get labile BP, fever, HR Sedation Raised CK and WCC Muscle rigidity and stiffness ```

Question 30

What is post-injection syndrome?

Answer 30

OD after a depot injection Monitor after injection Sedation Slurring Confusion Ataxia and Weakness