Medications Flashcards
What are some SSRIs?
Sertraline
Fluoxetine
Citalopram
What are some side effects of SSRIs?
Headache Nausea Increased motivation (for suicide) Weight Gain Agitation Anorexia
What are some SNRIs?
What are some side effects of SNRIs
Venlafaxine, Duloxetine
More severe side effects than SSRIs
Weight gain
Low Na+, high BP
What are some TCAs
What are some side effects of TCAs
What are they also used for?
Amytriptiline
Turned Off
Constipation
ANS effects - sweating, nausea, diarrhoea, anxiety
Neuropathic Pain
What is the standard dosage of SSRIs?
50mg Sertraline for depression (can go up to 100mg)
If anxiety/panic disorder then can give a high dose`
What are some NARIs?
What are some side effects of NARIs?
Reboxetine
Feel like i’m in a box) Sweating, Tachycardia, Constipation etc (ANS
What are some NaSSAs?
What are some side effects of NaSSa?
Mirtazapine
Weight Gain and increased appetite
Confusion
Tired
What is a specific risk of Citalopram?
Long QTc and hypokalaemia
How long do you take an anti-depressant for?
6 months after 1st episode goes
up to 2 years after second + episode
How long does it take SSRIs to start working
4-6 weeks
What is the 1st mood stabilizer?
What are some side effects of this mood stabilizers?
Lithium Carbonate
Leukocytosis Increased Thirst and urine Tremor (fine) HypoThyroid Increased weight Underactive Memory Mothers (teratogenic)
What are some atypical anti-psychotics?
What are some typical anti-psychotics?
Rispiridone
Olanzapine
Haloperidole
Chlorpromazine
Why do you use atypical anti-psychotics more than typical?
As they have fewer EPSEs
What are some side effects of anti-psychotics?
Increased prolactin - erectile dysfunction, dysmenorrhoea, gynaecomastia Tremor and Parkinsonism Sedation Nausea Headaches Weight Gain and glucose tolerence
What is the ADHD medication?
Side effects?
Ritalin
(Mehtyphenidate)
Growth restiction
BP raised
Seizures
Nausea and Headaches
When do you NOT use an AChE inhibitor?
COPD
What are some Alzheimers treatments?
Side effects?
Galantamine
Donepazil
Memantine
Bradycardia
Nausea
Syncope
AV Block
What anti-convulsants do you use in Bipolar?
Side effects?
Carbamezapine
Lamotrigine
Nausea
Sedation
HypoNa+
What is the 2nd line mood stabiliser
So
What is the 2nd line mood stabiliser
Sodium Valproate
Ataxia Liver Failure Pancreatitis Reversible Hair Loss Oedema Appetite Gain Teratogenic/Tremor Encephalopaty
What is the 2nd line mood stabiliser
Sodium Valproate
Ataxia Liver Failure Pancreatitis Reversible Hair Loss Oedema Appetite Gain Teratogenic/Tremor Encephalopathy
What is the abnormality with foetuses with Lithium?
Ebsteins Anomaly
What is the abnormality with foetuses with Valproate?
Neural tube defects
What do you use in refractory schizophrenia?
Clozapine
What are the side effects of Clozapine?
Weight Gain Agranulocytosis Increased Salivation Seizures Nausea
Can only do as an inpatient
What are the EPSEs and when do they come in?
Dystonia (days)
Akanthisia (weeks)
Parkinsonism
Tardive dyskinesia (months - years and are irreversible)
What is Tardive dyskinesia?
Involuntary, stiff, jerky, repetitive movements
Tongue sticking out, lip smacking
What is dystonia?
Painful, involuntary muscle spasms
e.g. torticollis
What is neuroleptic malignant syndrome?
Severe reaction to an anti-psychotic --> ICU You get labile BP, fever, HR Sedation Raised CK and WCC Muscle rigidity and stiffness
What is post-injection syndrome?
OD after a depot injection
Monitor after injection
Sedation
Slurring
Confusion
Ataxia and Weakness
