SubFUN2/membrane potential Flashcards
integral membrane proteins are _______ and extrinsic membrane proteins are ______
integral, extrinsic
______ mols can go through PM and _____ mols cant go through PM
nonpolar, polar
magnitude of plasma membrane potential depends on the degree of ________ separation
charge separation
cell membrane is more _____ inside than outside
negative
2 things that are responsible for RMP
- unequal distribution of K+, Na+ and A- b/w inside and outside of cell
(K+ and A- = ICF)
(Na+ = ECF)
- selective leakiness of PM to K+
K+ ECF/ICF
5/150 (mM)
Na+ ECF/ICF
150/15 (mM)
A- ECF/ICF
0/65 (mM)
___ Na+ ____, and ___ K+ ___
3, out, 2, in
at RMP, the inside becomes a little negatively charged because of the _______ transport of positive ions.
unequal, 3+ out and 2+ in
this only generates a small part of the potential diff though.
diffusion of __ out of the cell down conc. grad., est. by pump, is responsible for most of the potential. it leaves the inside more _____
K+, negative
2 membrane constituents that give neg. charge to inner membrane
PIP2 and PS
______ gradient acts as driving force for diff. of K+ out of the cell
chemical
the neg. charge inside acts as an ______ driving force drawing K+ back into the cell
electrical
equilibrium is when there is no ____ transport
net
