Subcutaneous Mycoses

Question 1

subcutaneous Mycoses

Answer 1

broad range of infections involving deeper layers of skin, muscle, bone, or connectvie tissues

Question 2

sporothrix schenckii

Answer 2

causes sporotrichosis in a variety of animals (humans, horses, dogs, and cats)

Question 3

Histoplasma capsulatum var. farciminosum

Answer 3

causes epizootic lymphangitis in equids

Question 4

agents causing oomycosis

Answer 4

• Aphanomyces
• Lagenidium
• Pythium
• Saprolegnia
• variety of disease in fish and mammals

Question 5

Miscellaneous conditions involving skin and subcutis

Answer 5

• chromoblastomycosis
• phaeohyphomycosis
• mycetomas

Question 6

Sporotrichosis

Answer 6

• rare disease
• manifest as a chronic, ulcerative lymphangitis of skin and subcutis
• affects horses, cats, dogs and humans
• systemic disease occurs in immunosuppressed humans and frequently cats
• cell mediated reactivity is significantly related to resistance

Question 7

adhesins

Answer 7

glycoconjugates in cell wall with affinity for extracellular matrix proteins

Question 8

lipids

Answer 8

inhibit phagocytosis by monocytes and macrophages

Question 9

melanin

Answer 9

protects from the effects of reactive oxygen intermediates within phagolysosome

Question 10

peptide- rhamnomannan

Answer 10

immunosupressive substances suppressing the liberation of proinflammatory cytokines

Question 11

sialic acids

Answer 11

inhibits uptake by phagocytes and is anti-complement

Question 12

Pathogenesis of sporothrix schenckii

Answer 12

• traumatic event
• ulcerating cutaneous nodule develops
• infectious process follows subcutaneous lymph channels
• suppurating ulcers are produced at intervals
• dissemination can occur to viscera, joints, and CNS in cats

Question 13

pyogranulomatous

Answer 13

-purulent center surrounded by: epithelioid cells, giant cells, and lymphocytes and plasma cells

Question 14

pathogenesis for Histoplasma capsulatum var. farciminosum

Answer 14

• infection through skin wound
• local skin nodule becomes abscessed and ulcerated
• adjacent lymphatics develop similar nodules
• hematogenous spread and visceral involvement is possible

Question 15

pythium

Answer 15

pyogranulomatous disease in a variety of animals

Question 16

lagenidium

Answer 16

• pyogranulomatous disease of dogs and cats

- clinically is the same as pythiosis

Question 17

aphanomyces

Answer 17

-ulcerative diseases of fish and crustaceans

Question 18

saprolegnia

Answer 18

systemic disease of fish

Question 19

pythium insidiosum

Answer 19

• causes ulcerative pyogranulomatous or fibrogranulomatous skin infections in horses, dogs, cattle, and cats
• mainly in stagnant waters in tropical and subtropical arease

Question 20

cutaneous pythiosis

Answer 20

• horses

- sparsely septated hyphae

Question 21

kunkers

Answer 21

dead macrophages and hyphe of the organism

Question 22

Chromoblastomycosis and Phaeohyphomycosis

Answer 22

-caused by dark-pigmented (dematiaceous) fungi

Question 23

chromoblastomycosis

Answer 23

• large pigmented sclerotic bodies are present
• rare in nonhuman mammals
• occur in frogs and toads

Question 24

phaeohyphomycosis

Answer 24

• hyphae are present
• sporadically in cats, dogs and other domestic animals
• CNS involvement is common

Question 25

mycetomas

Answer 25

• swelling
• granule formation
• discharge sinus tracts
• may be associated with bacteria
• reported in cattle horses dogs and cats

Question 26

associate fungi of mycetomas

Answer 26

• Pseudallescheria boydii
• Cocliobolus spiciferus
• Curvularia geniculata