Sub-clinical thyroid disease

Question 1

diagnosis

Answer 1

abnormal TSH with normal T3/4

Question 2

two types of subclinical thyroid disease

Answer 2

hypothyroidism

hyperthyroidism

Question 3

diagnosis of sub-clinical hypothyroidism

Answer 3

biochemistry

high TSH and normal T3/4

Question 4

what is the risk in sub-clinical hypothyroidism

Answer 4

progresses to overt hypothyroidism, especially if TPO antibody positive

Question 5

when is treatment advised in subclinical hypothyroidism?

Answer 5

if TSH >10

always treat in pregnancy to maintain normal TSH

Question 6

diagnosis of subclinical hyperthyroidism

Answer 6

low TSH and normal T3/4

Question 7

risk in subclinical hyperthyroidism

Answer 7

progression to overt

Question 8

when is subclinical hyperthyroidism often seen?

Answer 8

multinodular goitre

Question 9

what is subclinical hyperthyroidism associated with?

Answer 9

osteoporosis

AF

Question 10

when is treatment advised in subclinical hyperthyroidism

Answer 10

TSH <0.1
co-existing osteoporosis/fracture
or AF