Goitre

Question 1

define

Answer 1

this is any enlargement of the thyroid gland

Question 2

two types of goitre

Answer 2

diffuse

multinodular

Question 3

most common cause

Answer 3

lack of dietary iodine as reduced T3/4 causes a rise in TSH stimulating gland enlargement

Question 4

can goitres have a euthyroid state?

Answer 4

yes

Question 5

who is diffuse goitre common in?

Answer 5

women, puberty, young adults

Question 6

causes of diffuse goitre

Answer 6

ingestion of substance that limits T3/4, dyshormonogenesis (in children can cause cretinism) or iodiopathic

Question 7

presentation of diffuse goitre

Answer 7

mass
T3/4 normal
TSH high/upper limit of normal

Question 8

risks in multinodular goitre

Answer 8

rupture, haemorrhage, scarring and calcification

Question 9

mass effects in multinodular goitre

Answer 9

compression

cosmetic

Question 10

what can multinodular develop?

Answer 10

autonomous nodule (hyperthyroid)- risk of malignancy

Question 11

management of multinodular goitre

Answer 11

most can be left alone, RAI if significant hyperthyroidism and surgery if structural problems