Studies Flashcards

1
Q

NHAN ES 2

A

why A1C target is 7

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2
Q

Detect

A

retinopathy outcomes reduced if A1C =6.5

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3
Q

DCCT

A

intensive insulin regimen increased glycemic control but increased hypo by 3 fold. slowed progression of microvascular

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4
Q

EDIC

A

Showed that macro and micro complications are improved with intensive therapy

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5
Q

accord

A

if you treat >1.5% in pre-existing patient aim for reduction in 1 year not 6 months

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6
Q

ascend

A

Need to use more asprin in diabetic patients

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7
Q

UKPDS

A

BP control is more effective than glycemic control for outcomes + metformin decreases Glucose but no effect on complications

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8
Q

SAVOR

A

saxagliptin found to lead to HF, but is not a class effect

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9
Q

Canvas

A

Amputation risk in candaglifloxin

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10
Q

Carolina

A

GLP-1 vs sulf to show hypo improvement on GLP-1

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11
Q

ADOPT

A

rosiglitazone compared to metformin + glyberide, rosi was more effective but HF

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12
Q

Origin

A

insulin works but no help to cardio outcomes

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13
Q

Look ahead and Da Qing

A

exercise works

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14
Q

Advance + VADT

A

decrease A1C you decrease macrovascular effects

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