Insulin and other details

Question 1

Indication for statin therapy

Answer 1

Age >40
Age >30 with 15 years of diabetes
existing CV or renal issues

Question 2

Indication for statin + ACE/ARB

Answer 2

> 55 with CV risk factor (smoking, HTN, hyperlipidemia)
Or has
retinopathy
neuropathy
Left ventricular hypertrophy

Question 3

Indicatino for statin + ACE/ARB + SGLT2 or GLP-1

Answer 3

> 60 with >=2 CV risks
or
kidney disease (ACR >2 and GFR <60)
heart failure

Question 4

Detemir

Answer 4

Basal insulin (90min onset for 24 hours)

Question 5

Degludec

Answer 5

Basal insulin (90min onset for 42 hours) longest acting insulin

Question 6

Glargine

Answer 6

Basal insulin (90min onset for 24 hours)

Question 7

NPH

Answer 7

Intermediate
neutral protamine hagedorn insulin
onset 1-3 hours for 18 hours of action

Question 8

Lisprio

Answer 8

Bolus insulin (10min onset for 3-4.5 hours action)

Question 9

Glulisine

Answer 9

Bolus insulin (10min onset for 3-4.5 hours action)

Question 10

Aspart

Answer 10

Bolus insulin (9 min onset for 3-4.5 hours action)

Question 11

icodec

Answer 11

soon to come out once weekly basal insulin

Question 12

Are brands of insulin interchangeable

Answer 12

no

Question 13

Renally excreted drugs

Answer 13

Metformin
sulfnoureal
exogenous insulin

Question 14

Do any of the drugs cause cancer

Answer 14

no all of the evidence is bad and biased

Question 15

Drugs that can increase the risk of diabetes

Answer 15

Antiphycotics
antidepressants

Question 16

Drugs that can increase blood glucose

Answer 16

Decongestants
Steroids (prednisone)
protease inhibitors
calcineurin inhibitors

Question 17

Beta-blockers and diabetes

Answer 17

They can prevent epinephrine stimulated insulin release and increase BG
they can also inhibit liver glucose production and then hide some Sx of hypoglycemia (tremors, tachy)