structure and function of proteins Flashcards
primary structure
sequence of amino acid residues
secondary
the localised conformation of the polypeptide backbone
tertiary
the three-dimensional structure of an entire polypeptide, including all its side chains
quaternanry
the spatial arrangement of polypeptide chains in a protein with multiple subunits
types of secondaery structures
alpha helix
beta strands and sheets
triple helix
bonds in the polypeptide backbone
hydrogen
alpha helix
rod like
one poly p chain
are beta sheets parallel or antiparallel
both
what is the most abundant protein in vertebrates
collagen triple helix
collagen triple helix
component of bone and connective tissue
what proteins are in tertiary structures
fibrous and globular
fibrous proteins
Contain polypeptide chains organized approximately parallel along a single axis. They
consist of long fibers or large sheets
tend to be mechanically strong
are insoluble in water and dilute salt solutions
play important structural roles in nature
examples of fibrous
keratin of hair and wool
examples of globular
myo and haemoglobin
globular protiens
Proteins which are folded to a more or less spherical shape
they tend to be soluble in water and salt solutions
most of their polar side chains are on the outside and interact with the aqueous environment by hydrogen bonding and ion-dipole interactions
most of their nonpolar side chains are buried inside
nearly all have substantial sections of alpha-helix and beta-sheet
