oxidative phosphorylation Flashcards

1
Q

where does this occur

A

inner membrane of mitochondria

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2
Q

role of

A

making ATP by donating electrons to complees in membrane - comlexes being lipids/ protons

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3
Q

how does it begin

A

NADH and FADH wanting to donate their electrons

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4
Q

how do nadh and fadh enter mitochondria

A

via shuttles

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5
Q

what do electrons enter as if using the malate aspartate shuttle

A

NADH

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6
Q

what do electrons enter as if using the glycerol-3-phosphate shuttle

A

FADH2

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7
Q

what do fadh and nadh give their electrons to

A

complex I and complex II

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8
Q

complex I

A

flavin mononucleotide

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9
Q

comples II

A

succinate dehydrogenase

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10
Q

where do electrons from complexes I and II flow

A

directly to Coenzyme Q, which is also called ubiquinone

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11
Q

what does coenzyme q pass on the electrons to

A

to a series of cytochromes, which are proteins that contain heme groups.

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12
Q

cytochrome III - not important

A

made up of cytochrome b and cytochrome c1, and then electrons move over to cytochrome c, and from there the electrons get passed to complex IV, which is composed of cytochromes a and a3, which are together referred to as cytochrome oxidase

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13
Q

role of cytohcrome oxidase

A

transfers the electrons to the final electron acceptor, oxygen, making the oxygen electronegative enough to grab two protons - making a molecule of H20.

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14
Q

what happens if a cell doesnt recieve enough o2

A

electron transport chain gets interrupted and ATP synthesis doesn’t happen

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15
Q

what creates the electrical current

A

complexes rapidly passing electrons off to one another

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16
Q

role of electrical current

A

creates energy that drives complexes I, III, and IV to pump positively charged protons out of the mitochondria and into the space between the inner and outer mitochondrial membrane, creating a proton gradient across the inner mitochondrial membrane

17
Q

what complexes span the inner mitochodnrial membrane

A

complexes I, III, and IV

18
Q

is the gradient stable or unstable

A

considered unstable because the protons are always trying to equilibrate across the inner mitochondrial membrane, even though it’s totally impermeable to them

19
Q

how do proteins get across the membrane

A

use a special proton channel called F0, that’s attached to an enzyme called F1

20
Q

what does atp use to be pumped out of the mitochondria and into the cytoplasn

A

ATP/ADP anitporrt

21
Q

how mnay atp does 1 nadh that donates its electrons make

A

3 as it activtes 3 proton pumps; I,III and IV

22
Q

how many atp does fadh2 make

A

2 as it skips complex 1, and starts at complex 2, activating only 2 proton pumps - complexes III and IV

23
Q

is ETC controlled hormonally

A

no

24
Q
A