STRUCTURE AND F(X) OF LP. Flashcards

1
Q

STATE THE CONTENT OF LPL SHELL.

A

APOPROTEINS
PHOSPHOLIPIDS
NON ESTERIFIRED/ FREE CHOLESTEROL

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2
Q

STATE ONE PROPERTIES OF THE LPL SHELL.

A

AMPHIPATHIC

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3
Q

STATE THE CONTENT OF THE CORE.

A

TG
CHOLESTEROL ESTER

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4
Q

STATE THE F(X) OF APO A-1

A

TO ACTIVATE THE LCAT

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5
Q

STATE THE F(X) OF APO E

A

TO ACT AS A LIGAND FOR BINDING TO THE CELLULAR LP RECEPTOR

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6
Q

STATE THE FUNCTION OF APO A II

A

TO ENHANCE HEPATIC LIPASE ACTIVITY.

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7
Q

STATE WHERE THE APO A I CAN BE FOUND

A

HDL

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8
Q

STATE WHERE THE APO A II CAN BE FOUND

A

HDL AND CM

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9
Q

STATE WHERE THE APO E CAN BE FOUND

A

CM
IDL
VLDL
HDL

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10
Q

STATE THE FUNCTION OF APO B 100

A

ACT AS A LIGAND FOR BINDING TO THE CELLULAR LDL RECEPTOR

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11
Q

STATE THE FUNCTION OF APO C II

A

ACTIVATE LPL

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12
Q

STATE THE FUNCTION OF APO D

A

PROVIDE THE BINDING SITE FOR CHOLESTEROL IN CETP

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13
Q

STATE WHERE APO D CAN BE FOUND

A

HDL

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14
Q

STATE WHERE APO B 100 CAN BE FOUND

A

VLDL, IDL, LDL

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15
Q

STATE WHERE APO B 48 CAN BE FOUND

A

CM

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16
Q

STATE WHERE APO C II CAN BE FOUND

A

CM
VLDL
HDL

17
Q

WHICH LP HAVE THE HIGHEST PROTEIN PERCENTAGE?

A

HDL

18
Q

WHICH LP HAVE THE HIGHEST TG PERCENTAGE?

A

CM

19
Q

TRUE/FALSE:
A. CM HAVE THE HIGHEST DENSITY
B. HDL HAVE THE HIGHEST DENSITY
C. CM IS THE LARGEST IN SIZE
D. HDL IS THE SMALLEST IN SIZE.
E. CM IS HIGH IN PROTEIN AND TG.

A

A. FALSE (CM IS THE LOWEST DENSITY)
B. TRUE
C. TRUE
D. TRUE
E. FALSE (CM HIGH IN TG ONLY)

20
Q

TRUE/FALSE:
A. EACH LPL HAS THE SAME ELECTROPHORESIS MOBILITY.
B. PROTEINS ARE NEGATIVELY CHARGED
C. HDL MOVES THE LEAST TO ANODE
D. HDL IS HIGH IN PROTEIN
E. CM MOVES THE LEAST TO ANODE.

A

A. FALSE (EACH LPL HAS DIFFERENT ELECTROPHORESIS MOBILITY)
B. TRUE
C. FALSE (MOVES THE MOST)
D. TRUE
E. TRUE

21
Q

STATE WHERE DOES THESE LP ASSEMBLE AT:
A. CM
B. LDL
C. HDL
D. VLDL
E. IDL

A

A. CM: IN THE INTESTINAL EPITHELIAL CELLS
B. LDL: FROM VLDL REMNANTS OR IDL
C. HDL: LIVER AND INTESTINE
D. VLDL: LIVER
E. IDL: VLDL DURING VLDL DEGRADATION

22
Q
A