CELL TO CELL INTERACTION

Question 1

WHAT IS CELL TO CELL INTERACTION?

Answer 1

CELL TO CELL INTERACTION:
- IT IS IMPORTANT FOR CELL SIGNALLING TO OCCUR BETWEEN CELLS TO ENSURE THAT
> METABOLISM
> APOPTOSIS
> GENE EXPRESSION
> IMMUNE SYSTEM
> CELL MOVEMENT
> PROLIFERATION
> ION TRANSPORT
CAN OCCUR AND BE WELL MAINTAINED.
- THERE ARE 3 STEPS OF CELL TO CELL INTERACTION WHICH ARE:
> RECEPTION
> TRANSDUCTION
> RESPONSE
IN WHICH IT IS CALLED AS SIGNAL TRANSDUCTION PATHWAY

Question 2

STATE THE TYPES OF CELL TO CELL INTERACTION.

Answer 2

MNEMONIC: PAGE
P = PARACRINE
A.= AUTOCRINE
G = GAP JUNCTION
E = ENDOCRINE

Question 3

WHAT IS PARACRINE SIGNALING?

Answer 3

PARACRINE SIGNALLING
- IS A SIGNAL IN WHICH THE SECRETORY CELL IS RELEASED AND MOVE TO THE ANOTHER NEIGHBOURING CELL BY TRAVELLING A SHORT DISTANCE TO IT.
- EXAMPLES: HORMONES AND GROWTH FACTOR

Question 4

WHAT IS MEANT BY AUTOCRINE SIGNALLING?

Answer 4

AUTOCRINE SIGNALLING IS
- A KIND OF SIGNAL IN WHICH THE CHEMICAL SUBSTANCE IS PRODUCED BY THE SAME CELL THAT FUNCTION AS A TARGETED CELL FOR THE CHEMICAL MESSENGERS.
- EXAMPLE: GROWTH FACTOR, HORMONES, AND IL- 1

Question 5

WHAT IS MEANT BY DIRECT CONTACT?

Answer 5

• CELLS MAY COMMUNICATE BY DIRECT CONTACT IN WHICH THE SIGNALLING SUBSTANCES DISSOLVED IN THE CYTOSOL AND PASSES FREELY THE ADJACENT CELLS.

Question 6

WHAT IS MEANT BY ENDOCRINE?

Answer 6

ENDOCRINE IS A
- SIGNAL IN WHICH THE CHEMICAL MESSENGERS WILL BE RELEASED INTO THE BLOODSTREAM SO THAT IT CAN TRAVEL FOR A LONG DISTANCE TO REACH THE TARGETED CELLS BY EXPRESSING ON THE RECEPTORS.
- EXAMPLE: INSULIN, GLUCAGON AND EPINEPHRINE