Stroke Week: Clinical Management Flashcards

1
Q

What is meant by neuroplasicity?

A

Ability of brain to undergo biological changes; this could be small cellular changes or coritcal re-mapping. Neuoroplasticity allows us to:

  • Learn a new skill
  • Very important in recovery from stroke
  • Changes resulting from socioeconomic condition
  • Changes due to psychological stressors

etc….

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2
Q

What is the commonest cause of long term disability?

A

Stroke

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3
Q

Give an approximation of what % of strokes occur in under 65’s

A
  • 25% occur in under 65’s
  • 3% in under 40’s

*1 in 4 of us will have a stroke

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4
Q

Complete the sentence:

Stroke is the ____ leading cause of death in the developed world

A

3rd

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5
Q

What is the stroke pathway?

A

Document that details the core components of optimal service for someone who has suffered a stroke

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6
Q

Sumarise the stroke pathway

A
  • Pre-hospital
    • Hopefully patient will recognise signs of stroke (FAST) and ring 999
    • Priority 1 call for paramedics
    • Paramedics quickly assess patient
    • Paramedics use’ bat phone’ to alert hospital that they have a pt who may be having acute stroke
    • Stroke team is pre-alerted to be ready
  • Acute response and treatment on HASU
    • Stroke team meet pt in A&E and do the following:
      • Brief focused history
      • IV acess to get bloods
      • ECG
      • Baseline observations
      • NOTE: some of this may happen on route to CT
    • CT scan is interpreted there and then
    • Determine immediate treatment (thrombolysis [start giving whilst in CT scanner], bp lowering, thrombolectomy)
    • Pt transferred onto stroke unit for up to 72 hours
  • Life after HASU
    • Options: home, discharge at home with intensive therapy at home, rehabilitation, transfer to acute stroke ward
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7
Q

State some questions you need to ask yourself during the initial assessment of a stroke patient

A
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8
Q

What is the NIHSS?

A

National Institute of Health Stroke Scale: an assessment tool which gives a quantitative measure of stroke-related neurological deficit. It can be used as a measure of stroke severity.

It assess 11 key components:

  • Level of consciousness & communication
  • Eye movements
  • Visual fields
  • Facial palsy
  • Upper limb motor
  • Lower limb motor
  • Limb ataxia
  • Sensation
  • Langauage/aphasia
  • Dysarthria
  • Extinction/inattention

Score ranges from 0 to 42

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9
Q

Remind yourself of the Oxford clinical classification of strokes

A
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10
Q

State the NIHSS scores for:

  • No stroke
  • Minor stroke
  • Moderate stroke
  • Moderate to severe stroke
  • Severe stroke
A
  • 0= no stroke symptoms
  • 1-4= minor stroke
  • 5-15= moderate stroke
  • 16-20= moderate to severe stroke
  • 21-42= severe stroke
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11
Q

Is NIHSS a diagnostic tool?

A

NIHSS is NOT a diagnostic tool and it is NOT a substitution for a neuro exam

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12
Q

What Oxford classification of strokes does NIHSS underestimate (in terms of severity)?

A

POCs

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13
Q

How does fresh blood appear on CT scan?

A

FRESH blood on CT scan appears as bright white (high attenuation)

*If you did a CT scan 12 hours later, on a pt who had been given no treatment, there would be a dark area of infarcted brain (low attenuation)

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14
Q

CT scans of patients suffering an ischaemic stroke are often normal in the acute phase following a stroke; true or false?

A

True

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15
Q

Following immediate treatment of stroke, what happens on HASU

A
  • Thrombolysis completed (if started in CT scanner)
  • Observations every 15 mins
  • Junior doctor completes thorough assessment, checks bloods and head scan report

In the next 24hr:

  • Nurses complete nutrition & pressure area screening
  • Consultant review
  • Patient reviewed by physio, occupational therapy, speech & language therapy
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16
Q

Image is a summary of stroke pathway

A
17
Q

What drug is commonly used for thrombolysis in strokes?

A

Alteplase

18
Q

Discuss the criteria which you must consider when considering whether to give intravenous thrombolysis for a stroke

A
  • Clinical diagnosis of acute ISCHAEMIC stroke causing one or more of NIH score =/>4, binocular visual field deficit, swallowing deficit
  • Imaging consistent with ischaemic stroke
  • Symptom onset within 4.5 hours prior to initiation of thrombo
19
Q

What is the main complication of thrombolysis?

A

Bleeding (often in area where ischaemia occured)

20
Q

Only about 20% of patients are eligible for thrombolysis; state some other factors which make a bigger difference to the outcome for a patient

A
  • Prompt admission to stroke unit
  • Prompt secondary prevention
  • Early MDT
  • Maintaining homeostasis (hydration, nutrition, oxygenation, normoglycaemia)
  • Preventing complications
21
Q

If a patient is not eligible for thrombolysis (as we know only about 20% are eligible) we can ofer them early secondary prevention; state some of these treatments

A
  • Aspirin
  • Statin
  • Control bp (target <130/85)
  • Anticoagulate if in atrial fibrillation (DOACs used as first line)
  • Carotid surgery (e.g. carotid endarterectomy)
22
Q

State some ways in which we treat intracerebral haemorrhages

A
  • Reversal of coagulopathy
  • BP lowering if hypertensive
  • Surgery only if:
    • Haemorrhage with hydrocephalus
    • Lobar haemorrhage with GCS between 9 and 12
    • Cerebellar haemorrhage

In terms of what doesn’t work for ICH:

  • Surgery (most of the time)
  • Steroids
  • Platelets
  • Aspirin
  • VTE prophylaxis with compression stockings or LMWH
23
Q

State some potential complications following a stroke

A
  • Pneumonia (Sit up? Safe swallow?)
  • Seizures
  • Pressure sores
  • Dehydration/malnutrition
  • Constipation
  • Incontinece/retention
  • Depression
  • Spasticity
  • Venous thromboembolism