Stroke Flashcards
What must be excluded if FAST is present
hypoglcaemia
Initial management of TIA
300 mg aspirin daily
Imaging in TIA
Offer MRI for damage but not CT
Perform non0enhanced CT on suspected stroke patients with:
indications for thrombolysis or thrombectomy
on anticoagulant treatment
a known bleeding tendency
a depressed level of consciousness (Glasgow Coma Score below 13)
unexplained progressive or fluctuating symptoms
papilloedema, neck stiffness or fever
severe headache at onset of stroke symptoms.
Thrombolysis drug and window
Alteplase, 4.5 hours
Thrombolysis important factors:
treatment is started as soon as possible within 4.5 hours of onset of stroke symptoms and
intracranial haemorrhage has been excluded by appropriate imaging techniques
Early thrombectomy indications
It is within 6 hours of symptom onset, together with intravenous thrombolysis to people who have:
Acute ischaemic stroke and
Confirmed occlusion of the proximal anterior circulation demonstrated by computed tomographic angiography (CTA) or magnetic resonance angiography (MRA)
Later thrombectomy window
6-24 hours
When can later thrombectomy be indicated?
who have acute ischaemic stroke and confirmed occlusion of the proximal anterior circulation or
proximal posterior circulation demonstrated by CTA or MRA and
if there is the potential to salvage brain tissue, as shown by imaging such as CT perfusion or diffusion-weighted MRI sequences showing limited infarct core volume
Acute ischaemic stroke
Anticoagulant treatment
Haemorrhage must be excluded
aspirin 300 mg orally if they do not have dysphagia or
aspirin 300 mg rectally or by enteral tube if they do have dysphagia.
Continue aspirin daily 300 mg until 2 weeks after the onset of stroke symptoms, at which time start definitive long-term antithrombotic treatment.
offer PPI
acute venous stroke anticoagulation
Heparin and warfarin
Total anterior circulation stroke (TACS)
A total anterior circulation stroke (TACS) is a large cortical stroke affecting the areas of the brain supplied by both the middle and anterior cerebral arteries.
All three of the following need to be present for a diagnosis of a TACS:
Unilateral weakness (and/or sensory deficit) of the face, arm and leg Homonymous hemianopia Higher cerebral dysfunction (dysphasia, visuospatial disorder)
Partial anterior circulation stroke (PACS)
A partial anterior circulation stroke (PACS) is a less severe form of TACS, in which only part of the anterior circulation has been compromised.
Two of the following need to be present for a diagnosis of a PACS:
Unilateral weakness (and/or sensory deficit) of the face, arm and leg Homonymous hemianopia Higher cerebral dysfunction (dysphasia, visuospatial disorder)
Posterior circulation syndrome (POCS)
A posterior circulation syndrome (POCS) involves damage to the area of the brain supplied by the posterior circulation (e.g. cerebellum and brainstem).
One of the following need to be present for a diagnosis of a POCS:
Cranial nerve palsy and a contralateral motor/sensory deficit
Bilateral motor/sensory deficit
Conjugate eye movement disorder (e.g. horizontal gaze palsy)
Cerebellar dysfunction (e.g. vertigo, nystagmus, ataxia)
Isolated homonymous hemianopia
Lacunar stroke (LACS)
A lacunar stroke (LACS) is a subcortical stroke that occurs secondary to small vessel disease. There is no loss of higher cerebral functions (e.g. dysphasia).
One of the following needs to be present for a diagnosis of a LACS:
Pure sensory stroke
Pure motor stroke
Senori-motor stroke
Ataxic hemiparesis