Stroke Flashcards
What is a stroke ?
Neurological deficit of sudden onset
Lasting more than 24hrs
Of vascular origin
When does a transient ischaemic attack occur ?
<24hrs
What is the epidemiology of stroke ?
1/4 people worldwide will have a stroke One stroke every 5 mins in the UK 1/8 pateints die within first 30 days 3rd biggest killer in Scotland 50% of survivors ae dependent on others
What is the cause of stroke ?
Blockage with thrombus or clot
Disease of vessel wall
Disturbance of normal properties of blood
Rupture of vessel wall
What % have a ischaemic stroke ?
85-90%
What % have a haemorrhagic stroke ?
10-15%
What is the most important modifiable risk factor ?
Hypertension
What is the risk of smoking ?
2-fold increased risk of ischamic stroke
3-fold increased risk for sub-arachnoid haemorrhage
What are the risk factors for stroke ?
Hypertension Current smoker Waist to hip ratio Diet Diabetes Alcohol Stress/depression Cardiac causes Bleeding disorders Family history Ratio of ApoB to ApoA Oral contraceptive with high oestrogen
What is the pathophysiology of haemorrhage ?
Hypertension Amyloid Excess alcohol Hypocholesterolaemia Haemorrhagic transformation
What is the pathophysiology of iscahemic stroke ?
Ischaemia results from failure of cerebral blood flow to a part of the brain
Ischamia can be transient- TIA
Ischamia results in varying degrees of hypoxia and hypoglycaemia
What is anoxia ?
No oxygen
What can anoxia lead to ?
Results in infarction- leads to necrosis - completed stroke
What is the timing for stroke symptoms ?
Come on quickly
What are the symptoms of stroke ?
Motor (clumsy or weak limb) Sensory (loss of feeling) Speech- Dysphagia/ dysarthria Neglect/ visuospatial problems Vision- loss in one eye or hemianopia Gaze palsy Ataxia/ vertigo/ Incoordination/ nystagmus