Stroke Flashcards
prevalence stroke:
10/1000
Tia meaning and time lapse
transient ischemic attack
<24 h symp
CVA meaning and time lapse
cerobrovascular incident (symp >24H)
hemorrhagic stroke
blood leaks into brain
ischemic stroke
blood clot stops blood supply to area in brain
penumbra
the area surround a ischemic event such as trombotic or embolic stroke
ischemia occurs when…
blood flow is blocked, the release of free radicals causes damage to brain tissue
Etiology of Ischemic stroke (80% of cases)
trombosis –> embolism –> arterial occulsion –> brain infarction
Hemorrhagic stroke etiology (20%)
always intracranial
rupture of artery causes bleeding
two versions of hemorrhagic stroke
- intracerebral: hematoma directly in brain tissue
2. extracerebral: build up of blood anywhere within skull and meninges
Early treatment of stroke
thrombolysis, platelet aggregation inhibitors, anticoagulants
treatment within 3-4.5 hours
trombolysis with intravenous rtPA and IAT (risk = hemorrhage)
new is intra arterial thrombolysis, whats special?
it can be done in up to 6 hours.
Anterior circulation consists of (3)
internal carotid artery splits up into anterior cerebral artery and middle cerebral artery
posterior circulation consists of
vertebral arteries perforate transverse processus of cervical vertebrae via the foramen magnum. left and right fuse en form basilar artery. This one supplies the cerebellum and brain stem
circle of willis
site of large aneurysms
functional anatomy cortex.
Neocortex:
anteriorly:
posteriorly:
neocortex: mental functions
anteriorly: action related areas (frontal lobe)
posteriorly: perception areas (parietal, occipital and temporal lobes)
motor cortex
responsible for movement and arranged in anatomical order (called somatotopy)
somatotopy
arranged in anatomical order
the primary sensory area is arranged how?
topographically organized
how is the primary auditory cortex arranged?
tonotopy: all sound frequencies layed out over length of auditory gyrus
supply areas:
- anterior cerebral art:
- middle cerebral art
- posterior cerebral art
- anteromedial side
- lateral side and deep structures
- posterobasal side
Types of strokes (6)
- middle cerebral artery
- anterior cerebral artery
- carotid artery occlusion
- posterior cerebral artery stroke
- basilar artery stroke
- miscellaneous stroke