Stroke Flashcards
CT finding for carotid cavernous fistula
Dilated superior ophthalmic vein
Affective motor aprosodia
lesion to ____
symptoms
- lesion to nondominant frontal lobe
- Symptoms
- inability to express nonaffective or affective intonations in speech
Portion of brain most likely to be affected with prospagnosia
Fusiform gyrus
How to differentiate Vertebral artery from carotid artery dissection:
Both have (2)
Vertebral (3)
Carotid (4 )
Both have:
- Horners
- headache (“painful horners”)
Vertebral
- Cerebellar signs
- Decreased sensation to IL face
- Decreased sensation to CL body
Carotid
- Amarosis Fugax
- pulsatile tinnitus
- decreased taste
- more localized weakness.
Compare Hunt / Hess score versus World federation of neurosurgical societies (WFNS) scale
Aneurysms of what artery are most likely to compress CN III
Posterior communicating artery
ABCD2 scoring system + 2- and 7-day risk for stroke at each risk level
Low risk (1-3)
- 2-day: 1.0%
- 7-day: 1.2%
Moderate risk (4-5)
- 2-day: 4.1%
- 7-day: 5.9%
High risk (6-7)
- 2-day: 8.1%
- 7-day: 11.7%
Mechanism of action:
Aspirin
Clopidogrel / Ticlopidine
Abciximab
Tirofiban
Eptifibatide
- Aspirin:
- Irreversible binding to cyclooxygenase
- Leads to decreased synthesis of thromboxane A2
- Clopidogrel / Ticlopidine
- Irreversible inhibition of ADP
- Abcimixab
- monoclonal antibody which inhibits Glycoprotein IIb/IIIa complex formation
- Tirofiban
- Arginine-Glycine-Asperginine sequencs binds to glycoprotein IIb/IIIa complex
- Eptifibatide
- Analogue of carboxy-terminal of Delta chain of fibrinogen
CODE STROKE!
Inclusion criteria (3)
Absolute Contraindications regardless of time
Contraindications if within 3-4.5 hour window
- Inclusion criteria
- Symptoms consistent with ischemic stroke with measurable neurologic defecit
- Last known Normal <4.5 hours ago
- Age >18 years
- Absolute contradindications: ABCDE
- history of Aneurysms or AVM
- Active Bleeding
- intracranial Injuries or stroke within 3 months
- bleeding Diathesis (such as anticoagulants / coagulopathies) with abnormal coag profile
- Endocarditis
- Contraindications at 3-4.5 hours: also ABCDE
- Age >85 years
- Bad stroke (NIHSS >25)
- CT shows multilobar stroke
- bleeding Diathesis (regardless of coagulations)
- Ever had a stroke or Diabetes
Patient with left sided ptosis has this MRI
What other features would you suspect? (8)
- Vomiting / vertigo / nystagmus
- IL ataxia, dysmetria, dysdiadochokinesia
- IL pain / temp loss to FACE
- IL Horners
- CL pain / temp sensation to BODY
- Dysarthria, pharyngeal sx (hoarsenss)
- Absent Gag
- Palatal myoclonus
Breathing abnormalities and stroke
Apneustic
Ataxic
unilateral hemispheric
complete apnea
Apneustic: pontine lesion
Ataxic: Medullary (think “MAX”)
unilateral hemispheric: Cheyne-Stokes (though not specific)
complete apnea: high spinal cord lesion
Patient presents with cerebellar ataxia, Vertigo, hearing loss, and tinnitus
What vessel was injured?
What if he didn’t have deafness?
AICA
If no deafness can also be PICA (wallenberg syndrome)
Lesion responsible for dressing apraxia
Right parietal
Contralateral Face + Arm Weakness = Damage to…
Reurrent artery of Heubner (branch of ACA)
Why isn’t hydralazine used as first-line for lowering BP in the setting of stroke?
Selective arteriolar vasodilation > reflex tachycardia > can lead to myocardial injury
ASPECT scores
- start at 10, subtract 1 for each segment involved
Patient with dementia has this imaging finding. What is the most common presentation of this disorder?
Cerebral amyloid angiopathy, most common presentation = spontaneous lobar hemorrhage
Strokes presenting with confabulation, memory deficits, and confabulation
Mamillary body strokes
Causes of drug-induced necrotizing central nervous sstem vasculitis
Amphetamines
Blood pressure requirements for administrating IV tpa
Initial
within 24 hours
Initial
- 185/110
Within 24 hours
- 180/105
Patient presents with transient blindness for several minutes after being exposed to bright light. History of coronary artery bypass
What is this worrisome for?
Carotid occlusive disease
Mnemonic for Lateral Medullary syndrome
Aka Wallenberg syndrome
“Look at the Water to make sure it isn’t hot, Put In (PICA) your IL hand and rub it on your CL face (CL pain/temp to body, IL pain/temp to face); This is hard because of the IL ataxia. “you can’t cry out (hoarsness), and if you could it wouldn’t make sense (IL ataxia).
Someone comes in with because he burned his right hand and didn’t know he cut his left cheek while shaving
What was damaged?
What else would you look for?
PICA (Lateral medullary syndrome)
Hoarseness
Dysarthria
IL ataxia