Neuroimmunology Flashcards

1
Q

Cervical x-ray finding associated with rheumatoid arthritis

A

Atlantoaxial dislocation

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2
Q

Paraneoplastic Conditions: Amphiphysin

Features (2)
Associated cancers (2)
A

Amphiphysin

Features:

  • Encephalomyelitis
  • stiff person syndrome

Associated Cancers

  • SCLC
  • Breast
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3
Q

Paraneoplastic syndromes: CRMP-5(CV2)

Associated symptoms (7)

Associated cancers (2)

A

CRMP-5 (CV2)

Associated symptoms

  • Limbic encephalitis
  • peripheral neuopathy
  • cerebellar degeneration
  • Encephalomyelitis
  • chorea
  • Chronic GI
  • Optic Neuropathy

Associated cancers

  • SCLC
  • Thymoma
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4
Q

Paraneoplastic antibodies: Hu

Symptoms (5)

Associated cancers

A

Symptoms

  • encephalomyelitis
  • sensory neuropathy
  • cerebellar degeneration
  • limbic encephalitis
  • opsiclonus-myoclonus syndrome

Associated cancer: SCLC

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5
Q

Autoantibodies: Ma2

Symptoms (3)

Associated cancers (2)

A

Symptoms

  • Limbic encephalitis
  • brainstem encephalitis
  • Diencephalic cencephalitis

Cancers

  • Testicular Cancers
  • Lung
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6
Q

Autoantibodies: Ri (Anna-2)

Symptoms (3)

Cancers (3)

A

Symptoms

  • Ataxia
  • Opsoclonus-myoclonus
  • brainstem encephalitis

Associated cancers

  • Breast
  • Gynecologic
  • SCLC
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7
Q

Autoantibodies: TA

A

Associated conditions

  • Limbic encephalitis
  • Brainstem dysfunction

Associated cancers: testicular

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8
Q
Autoantibodies associated with:
Cerebellar degeneration (4)
A

TR+mGLUr1 (hodgkin’s lymphoma)

Yo (ovary / breast)

Zic4 (SCLC)

CRMP-5 (SCLC / Thymoma)

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9
Q

Autoantibodies associated with:

Brainstem dysfunction / encephalitis (3)

A

TA (testicular)
RiAnna-2 (Breast / Gynecologic / SCLC)
Ma2 (testicular / Lung)

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10
Q

Autoantibodies associated with:

Sensory neuropathy (2)

A

CRMP-5 (SCLC / Thymoma)

Hu (SCLC)

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11
Q

Autoantibodies associated with:

Limbic encephalitis (4)

A

CRMP-5 (SCLC / Thymoma)

Hu (SCLC)

Ma2 (Testicular / lung)

Ta (testicular)

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12
Q

autoantibodies associated with:

Encephalomyelitis (3)

A

Amiphysin (SCLC / Breast)

CRMP-5 (SCLC / Thymoma)

Hu (SCLC)

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13
Q

Autoantibodies assocaited with:

Stiff-person syndrome

A

Amphiphysin (SCLC / Breast)

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14
Q

Antibodies associated with Opsoclonus-myoclonus (2)

A

Ma (Testicular / Lung)

RiAnna-2 (Breast / Gyn / SCLC)

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