stress Flashcards

1
Q

stress

A

any significant disturbance in homeostasis

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2
Q

stressor

A

stimulus/agent that causes stress, or change in homeostasis; anything that changes overall arousal whether positive or negative

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3
Q

stress response

A

physiological, behavioral, or psychological response to stressor with a goal of re-establishing homeostasis

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4
Q

how stress is measured in animals

A
  1. restraint
  2. forced swim
  3. cold exposure
  4. dominance hierarchies **both alpha and sub stressed, magnitude of stress depends on species
  5. predator
  6. fear conditioning
  7. chronic variable stress
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5
Q

Canon: emergency theory of adrenal function

A

epinephrine released in response to stressor from adrenal medulla as a means of adapting to that stress

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6
Q

epinephrine and fight or flight response

A

automatic and endocrine responses that prepare an individual to fight or flight from a real or perceived attack, harm, or threats to survival

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7
Q

sympathetic NS anatomy

A
  • thoracic lumbar
  • short PRE ganglion neurons, long POST ganglion neurons
  • short pre ganglion neurons synapse onto sympathetic chain ganglion
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8
Q

parasympathetic NS anatomy

A
  • cranial and sacral

- long pre ganglion neurons, short post ganglion neurons

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9
Q

HPA axis

A

CRH–> ACTH–> cortisol (neg feedback on AP and Hypo)–> effects on metabolism (feed back on stressor to bring back body to homeostasis)

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10
Q

effects of cortisol

A
  1. maintain blood pressure
  2. regulate cardiovascular function
  3. increase blood glucose (decrease insulin)–> want to use, not store energy
  4. regulate metabolism
  5. decrease immune response (energy intensive)
  6. decrease inflammation
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11
Q

adaptive nature of stress response

A
-increase immediate available energy 
increase oxygen 
decrease blood flow to areas not necessary for movement 
inhibit energetically taxing processes 
decrease pain perception 
enhance sensory functioning and memory
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12
Q

pathological signs of stress

A

peptic ulcers
adrenal hypertrophy
atrophy of thymus, spleen, lymph nodes
negative effects on cognition and memory

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13
Q

chronic stress and dendritic morphology

A

decrease in DS length, dendritic spine density, and change in shape

HOWEVER can be reversed with rest and recovery (removal of stressor)

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14
Q

cortisol and impairment of feedback pathway in hippocampus

A

chronic stress–> excessive release of cortisol–> damage of hippocampal neurons that feed onto the hypothalamus (can’t tell hypothalamus to turn of secretion of RH)–> unchecked CRH, ACTH, and cortisol–> more cortisol–> more destruction…

in healthy person, cortisol feeds back on hypo and AP to shut off RH and tropic hormones

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15
Q

psychosocial elements of chronic stress

A
  1. sense of control
  2. predictability
  3. frustration outlets
  4. social supports
  5. social rank (rats sub> alpha; dogs and mongooses a>s)
  6. social stability
  7. early life experiences
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