Stress 1 Flashcards
What does stress tell us about our bodies?
Our body is preparing us for survival (fight or flight)
What can stress people?
- Exams
- Grades
- Deadlines
- Traffic
- Family relationships ̈ Facebook posts
- Careers
What is not a significant stressor in our lives now compared to our evolutionary past lives?
1) Being eaten/preyed on
2) Catching and hunting food in the wild
What stresses a zebra?
1) Serious physical injury
2) Predators (e.g. lions)
3) Starvation
Who wrote a book on “Why zebras don’t get ulcers”?
Sapolsky 1994
Sapolsky 1994 wrote….?
“Why zebras don’t get ulcers”
What is stress?
A situation that ‘causes stress’ to a system
(e.g. aversive event)
Simply = something in the environment that causes us to respond in a specific way (stressed)
Is stress precise?
Stress is imprecise (a term used too often in everyday language; lost its true meaning)
A situation that ‘causes stress’ to a system
(e.g. aversive event)
What is this?
Stress
The way we respond to a stressor
What is this?
Stress reactivity
What is stress reactivity?
The way we respond to a stressor
2022 Liz Truss - ended up avoiding PM questions when under substantial stress
Is this high or low stress reactivity?
High stress reactivity (did not endure criticism and hate well)
2011 Donald Trump - after a scathing review, Trump sent the journalist a picture of herself with ‘face of a dog!,’ scrawled on it.
Is this high or low stress reactivity?
Low stress reactivity (endured criticism and hate well)
How does our body change when we feel stress?
- Changes in breathing
- Exacerbate existing mental health conditions
- Changes in eating behaviour
- Diarrhea/ constipation
How does our breathing change when we feel stressed?
We feel more anxious when there’s a stressor around
- Increased risk of asthma attack/ emphysema
- Hyperventilation during stress – increased risk of a panic attack in those with panic disorder (especially people with psychiatric disorders)
How does our eating behaviour change when we feel stressed?
We might eat more or less than usual
e.g. During exam season, you feel more stressed than usual and thus, eat a lot more junk food than usual
What does stress predict?
Mental health conditions
Based on DSM, many conditions are brought about by highly stressful points in one’s life
What is it called when stress is prolonged?
Chronic stress
What is Chronic stress?
When stress is prolonged and your body is in constant fight-or-flight mode
What happens to our bodies if we experience chronic stress?
- Muscles of the body are in a constant state of guardedness (tensed)
- Tension-type headaches/ migraines
- Long-term heart/ blood problems which leads to Hypertension and increased risk of a Heart attack
Why study stress?
Study the evidence that actually shows that health problems and chronic stress symptoms are more likely to occur due to stress
Who conducted a multi-ethnic study of atherosclerosis?
Everson-Rose et al. 2014
What did Everson-Rose et al. 2014 do to investigate the effects of stress?
1) Did a multi-ethnic study of atherosclerosis (heart problems)
2) A population-based study of 6749 adults (45-84 years old, free of cardiovascular disease)
3) Did a follow-up over an average of 8.5 years (to observe what happened to them)
4) Stress was measured as a burden in 5 domains to try and predict whether the participants went on to have heart problems at the longitudinal, follow-up point
What were the 5 domains of stress burden in Everson-Rose et al.’s study?
- Health problems
- Health problems of others (whether they had to care for other people)
- Job or ability to work problems
- Relationships
- Finances
What did Everson-Rose et al. discover about chronic stress?
Chronic stress (i.e. burden) at baseline predicted an increased likelihood of stroke over the follow-up period (10% increase)
Held after accounting for race, age, sex, and education.
Simply = If you take a measure of the amount of chronic stress in people’s lives, you can predict atherosclerosis (heart problems over time)
10% increase in the likelihood of a stroke in those who have high levels of chronic stress
Who unintentionally discovered that living things have a stress response?
Walter Cannon (1871-1945)
Who coined the term fight or flight response?
Walter Cannon (1871-1945)
What did Walter Cannon (1871-1945) do in his experiment?
- Experimented with rats
- Put rats in a stressful situation (e.g. fighting with other rats or constantly moving their cages when they’re sleeping)
Is fight or flight acute or chronic stress response?
Acute stress response
What happens in fight or flight?
1) Arousal (something in the environment stresses you)
2) Increased blood supply and sugar (draining of BS to the superficial parts of the body; face becomes pale; BS floods into the deeper muscles for you to run or fight back)
3) Violent burst of energy (constriction of vessels going to the superficial parts of the body and dilation of the vessels going into deeper muscles)
Is fight or flight useful for short-term or long-term stressful tasks?
Short-term stressful tasks
When fight or flight is prolonged/continuous, what happens?
We experience negative consequences
e.g. severe withdrawal behaviour
e.g. increased risk of depression and anxiety
e.g. peptic ulcers
An injury is an example of what type of stressor?
Physical and acute stressor
Hunger and cancer are examples of what type of stressor?
Physical and chronic stressor
A deadline for an assignment is an example of what type of stressor?
Psychological and acute stressor
Chronic work pressure (lots of deadlines one after another) is an example of what type of stressor?
Psychological and chronic stressor
Humiliation is an example of what type of stressor?
Social and acute stressor
Chronic isolation is an example of what type of stressor?
Social and chronic stressor
In the 1900s, what were the 4 main causes of morality/death?
- Pneumonia
- Tuberculosis
- Influenza
- Childbirth (young women)
From 2007 onwards, what was (and is) the main cause of morality/death?
Cumulative damage (things predicted by chronic stressors; acute stressful incidents that have turned into longer-term issues that build over time)
- Heart disease
- Cancer
- Cerebrovascular disorders
Things predicted by chronic stressors; acute stressful incidents that have turned into longer-term issues that build over time
This is known as…?
Cumulative damage
What parts of our body are involved in the stress system/response?
HPA axis
1) Hypothalamus
2) Pituitary gland
3) Adrenal gland
What is the HPA axis?
1) Hypothalamus
2) Pituitary gland
3) Adrenal gland
Parts of the body involved in a stress response/system
Describe the stress response system/HPA axis.
1) We perceive a threat in the environment
2) Threat causes the hypothalamus to release hormones into the bloodstream (CRH hormone)
3) The CRH passes through the portal veins/small vessel to get to the pituitary gland (anterior pituitary)
4) When CRH is received by the AP, it triggers the release of the ACTH hormone
5) The ACTH hormone passes through the bloodstream and goes down the adrenal cortex
6) When ACTH is received by the adrenal cortex, it triggers the release of cortisol
7) Cortisol calms the stress response system overtime (anti-inflammatory) and slowly rises to the peak rate of 15-20 mins
Where is the adrenal cortex located?
Just above the kidneys
Describe the stress response system/HPA axis in simple terms
1) Perceived threat in the environment
2) Threat triggers the release of CRH from the hypothalamus
3) CRH travels through small vessels to the anterior pituitary
4) CRH triggers the release of ACTH from the anterior pituitary
5) ACTH travels through the bloodstream to the adrenal cortex
6) ACTH triggers the release of cortisol from the adrenal cortex
7) Cortisol is an anti-inflammatory steroid which calms the stress response system down over time
What is cortisol used to measure in experiments?
The amount of stress that someone’s experiencing
Where is the hypothalamus located?
Centrally located in the brain
What is the hypothalamus involved in?
Homeostasis
What are the 3 types of homeostasis is the hypothalamus involved in?
1) Thermoregulation (our body sweats and/or pants if too hot and shivers if too cold
2) Circadian rhythms (receive projections from the back of the eye which tell us how much light there is around; tells us seasonal changes and day/night times)
3) Satiety & feeding (whether we are hungry or not)
Who examined the effects of lesions on cats?
Bard 1928
What did bard 1928 do in his study on the hypothalamus?
- Examined the effects of lesions on cats
- Removed most of the cerebral cortex either with or without the hypothalamus
What did bard 1928 discover in his study on the hypothalamus?
Cats who only had their cerebral cortex removed and not their hypothalamus showed undirected rage when regions of the brain are stimulated
Cats who only had their cerebral cortex removed as well as their hypothalamus showed no rage when regions of the brain are stimulated
What did bard’s findings on the hypothalamus suggest about the involvement of the hypothalamus in fight or flight response?
- The hypothalamus is clearly involved in ‘fight or flight response
- Because when the hypothalamus was removed, there was no rage (no f or f response when stressed) but when it was intact there was rage (there was a f or f response)
- The hypothalamus also releases stress hormones (corticotropin-releasing hormone (CRH))
CRH is released by ….. and travels through ……. to the …….
1) Hypothalamus
2) Small blood vessel
3) Pituitary gland
The master gland involved in different functions is known as…?
The pituitary gland
Where is the pituitary gland located?
Located beneath the hypothalamus
How much does the pituitary gland weigh?
0.5g
What hormones do the pituitary gland release List 4
1) Somatotrophins (e.g. HGH; growth hormones)
2) Thyrotrophins (TSH; metabolism hormones)
3) Gonadotrophins (LH, FSH; fertility hormones)
4) Corticotropins (adrenocorticotropic hormone - ACTH; stress response hormone)
What is the stress response hormone released by the pituitary gland?
ACTH
ACTH is released by…?
The pituitary gland
Which hormone passes through the blood stream and goes down the adrenal gland?
ACTH
Where are the adrenal glands located?
On top of your kidneys