Streptococcus pyogenes

Question 1

gram staining

Answer 1

gram+

Question 2

shape

Answer 2

spherical

Question 3

compared to staphylococcus aureus

Answer 3

smaller and more void 空洞

Question 4

arrangement

Answer 4

in chains

Question 5

spore forming

Answer 5

non-spore forming

Question 6

mobility

Answer 6

non-motile

Question 7

catalase?

Answer 7

absent

Question 8

where can it be found in human body

Answer 8

upper respiratory tract

Question 9

what hemolysis? what color

Answer 9

beta hemolysis (complete lysis of RBC), clear (transparent zone)

Question 10

pharyngitis majority group of patients

Answer 10

school age children (5-15 years of age)

Question 11

pharyngitis symptoms

Answer 11

person-to-person transmission (eg coughing and sneezing)
acute sore throat
malaise
fever
headache

Question 12

impetigo 膿痂疹 cause

Answer 12

Group A Strep skin colonization plus minor trauma like insect bite

Question 13

impetigo transmission

Answer 13

spread locally via scratching and to others by direct contact or shared fomites

Question 14

impetigo is found to be associated with what substances?

Answer 14

M protein

Question 15

symptoms

Answer 15

small vesicle (up to 1cm) surrounded by an area of erythema (abnormal redness of skin)
vesicle enlarges over a period of days–> become pustular and eventually breaks to form a yellow crust

Question 16

streptolysin function

Answer 16

produce tissue injury and toxic to phagocytic cells

Question 17

C5a peptidase function

Answer 17

inactivate the complement C5a and blocks chemotaxis of polymorphonuclear neutrophil–> allow streptococcal infection to continue

Question 18

Streptokinase and hyaluronidase

Answer 18

facilitates the spread of streptococci in tissues

Question 19

symptoms of Streptococcal toxic shock syndrome

Answer 19

myalgia
chills
severe pain at infected site

Question 20

symptoms of necrotizing fasciitis 壞死性筋膜炎 and myonecrosis 肌壞死

Answer 20

nausea
vomitting
diarrhea
hypotension
shock
impaired renal function (azotemia)
bacteremia

Question 21

symptoms of scarlet fever

Answer 21

sore throat
fever
skin rash
white coating on tongue

Question 22

treatment of Streptococcus pyogenes

Answer 22

Penicillin G
erythromycin and azithromycin if allergic