Listeria monocytogenes

Question 1

gram staining

Answer 1

positive

Question 2

shape

Answer 2

rod-shaped

Question 3

having flagella?

Answer 3

yes

Question 4

mobility

Answer 4

motile in low temperature

Question 5

spore forming

Answer 5

non-spore forming

Question 6

which type of hemolysis

Answer 6

beta-hemolysis

Question 7

does it love or hate oxygen

Answer 7

fasculative

Question 8

how can it grow slowly in low temperature?

Answer 8

presence of RNA helicase

Question 9

consequence of fetal infection

Answer 9

stillbirth

Question 10

pathogenesis

Answer 10

Internalin mediates the attachment of L
monocytogenes to the enterocytes by binding the
host cell receptor (E cadherin) and enters in an
endocytotic vacuole
Listerolysin O ( lyses the vacuole, L
monocytogenes escape to the cytoplasm
By actin polymerization, L monocytogenes move
along the cytoskeleton filaments and propel
throughout the cytosol
It reaches the edge of cell, protrudes and invades
adjacent cells
Process continues with escape to submucosa and
bloodstream invasion

Question 11

Treatment

Answer 11

ampicillin
Trimethoprim-sulfamethoxazole