Stomach Flashcards
where are the parietal cells located
Body of the stomach
largest artery to the stomach
left gastric artery
What is the nerve in the posterior fundus that is easily missed during truncal or highly selective vagotomy
criminal nerve of grassi
What nerve innervates gastric contraction
vagus nerve from parasympathetic fibers
Location of gastric ulcers associated with increase gastric acid production
pylorus
type II and III
Most serious complication of EGD
esophageal perforation
Advantage of double contrast upper GI series compared to EGD
- diverticula
- fistula
- tortuosity or stricture location
- size of hiatal hernia
Gold standard for H. pylori diagnostic
Histologic examination of antral biopsy with special stains
Test for eradication of H. pylori
urease breath test
Blood type more common duodenal ulcer
type O
Blood type more common gastric ulcer
Type A
Peptic ulcer formed after severe burn injury
curling ulcer
Peptic ulcer formed after severe brain injury
cushing ulcer
Types of ulcer associated with increased gastric acid secretion
Type II and III
Types of ulcer associated with normal or decreased gastric acid secretion
Type I and IV
Ulcer located in the Angularis Incisura
Type I - most common
Ulcer located in the angularis incisura but with accompanying duodenal ulcer
Type II
Ulcer located in the Prepyloric area
Type III
Ulcer located in the GE junction
Type IV
Ulcer caused by NSAID and can occur anywhere
Type V
Indications of endoscopy in PUD
- patient > 45 y.o
- patient regardless of age with alarm symptoms
a. weight loss
b. dysphagia
c. anemia
d. bleeding
e. recurrent vomiting
Location of High risk ulcer for massive bleeding
- lesser curvature of stomach with erosion to left gastric artery
- posterior duodenal ulcer with erosion to gastroduodenal artery
This surgery is done by severing the proxial 2/3 of vagal supply to the stomach, preserves the antrum and pylorus and remaining abdominal viscera
highly selective vagotomy
parietal cell vagotomy
proximal gastric vagotomy
This is a posterior truncal vagotomy and anterior seromyotomy
Taylor procedure
This procedure is useful for patients who require pyloroduodenotomy to deal with the ulcer complication
truncal vagotomy + pyloroplasty
This is a good choice in patients with gastric outlet obstruction
truncal vagotomy + gastrojejunostomy
Where is gastrin produced
antral G cells
What is the most potent inhibitor of gastrin
luminal acid
what is the most potent stimulatn of gastrin
luminal peptide and amino acid
Where does 90% of Zollinger Ellison Syndrome occur
Pasaro’s Triangle
Gastrinoma triangle
What are the boundaries of Pasaro’s Triangle
- junction of cystic and common bile duct
- 2nd and 3rd segment of duodenum
- junction of body and neck of pancreas
Confirmatory Test for ZES
Posivie secretin stimulation test
What other laboratory test are needed to check for ZES
serum calcium and PTH to rule out MEN1
- parathyroid
- pituitary
- pancreatic or duodenal tumors
What is the preoperative imaging of choice for gastrinoma
Somatostatin receptor scintigraphy
Where is somatostatin produced
D cells located through out the gastric mucosa
Major stimulus for somatostatin release
antral acidification
What inhibits somatostatin release
acetylcholine
A type of ulcer that is due to inadequate gastric mucosal blood flow
Stress ulcer
Which risk factor has no role in gastric adenocarcinoma
ALCOHOL!
Type of polyps associated with gastric carcinoma
- hyperplastic
2. adenomas
Protective factors of gastric carcinoma
- vitamin c
- aspirin
- high in fruits and vegetables
What is the most common precancerous lesion in gastric carcinoma
atrophic gastritis
What is the most important prognosticating factor or gastric cancer
lymph node involvemet
depth of tumor invasion
Another name for linitis plastica
Scirrhous Tumor
A name for palpable umbilical nodule in gastric CA
sister mary and joseph nodule
A name for palpable nodule in the pouch of douglas
blumer nodes
sign of drop metastases
Only curative treatment of gastic cancer
radical subtotal gastrectomy
goal of resecting gastric cancer
R0 resection
grossly negative margin of at least 5 cm
What is the most common site for primary GI lymphoma
stomach
Treatment of gastric lymphoma
chemotherapy
It is equivalent to surgery
It is a submucosal solitary slow growing tumor arising from the interstitial cells of cajal
GIST
Most common cell type of GIST
epithelial cell stromal GIST
Marker for GIST
(+) c - kit
Treatment of GIST
wedge resection with clear margins
Treatmet of unresectable or metastatic GIST
Imatinib - tyrosine kinase inhibitor
Mode of metastasis of GIST
hematogenous: liver and lungs
Most common type of polyp
hyperplastic (regenerative) polyp - 75%
What is the cause of afferent limb obstruction (blind loop syndrome)
billroth II - distal gastric resection followed by gastrojejunal anastomosis
What is the treatment of afferent limb obstruction?
conversion of billroth II to rouy en y gastric bypass
What is roux syndrome
delayed gastric emptying
Endoscopy: Bezoar formation
This presents with hypochloremic, hypokalemic, metabolic alkalosis
Gastric outlet obstruction
This disease occurs when there is delivery of a hyperosmolar load into the small bowel
Dumping Syndrome