Head and Neck Flashcards
most common preventable risk factor in the head and neck CA
tobacco and alcohol
It is a second tumor detected within 6 months of the diagnosis of the initial primary lesion
synchronous neopllasm
It is a second tumor detected more than 6 months of the diagnosis of the initial primary lesion
metachronous neoplasm
What is the initial evaluation of patients with primary CA of head and neck
panendoscopy
Most common location of squamous cell CA of the lip
lower lip
What nerve is involved when there is paresthesia of the lips
mental nerve
treatment of squamous cell cancer of the lip
T1 - T2: resection = radiation
T3 - T4: surgical excision with histologic confirmation of tumor free margin and post operative radiation
What are the indications for supraomohyoid neck dissection
- tumor greater than 4 cm
- desmoplastic tumor
- perineural invasion
Tongue cancer with lingual nerve involvement causes
ipsilateral paresthesia
Tongue cancer with hypoglossal nerve involvement causes
deviation of tongue on protrussion and fasciculations
Most common location of tongue cancer
lateral and ventral surfaces
Treatment of tongue cancer
T1 - T2 - wide local excision
Base of Tongue - partial glossectomy with supraomohyoid dissection (N0) or MRND (N+)
Featurs of plummer vinson syndrome
- cervical dysphagia
- IDA
- atrophic oral mucosa
- brittle spoon finger nails
Treatment of tumor of alveolus and gingiva
- minimal bone invasion - mandibular resection
2. medullary cavitiy invasion - segmental mandibulectomy
Treatment of tumors of nasopharynx
chemotherapy
Most common nasophryngeal malignancy in the pedatric age group
lymphoma
Lymphatic spread of nasopharynx
- bilateral regional
2. posterior triangle (level 5)
Lymphatic spread of oropharynx
- upper and lower cervical lymphatics (level 2, 3, 4)
2. retropharyngeal spread
Lymphatic spread of hypopharynx
- bilateral regional
2. mid and lower cervical lymphatics (level 3, 4)
Tumors of the oropharynx are radiosensitive
Tumors of the oropharynx are radiosensitive
Where does larngeal granuloma usually occur?
posterior larynx on the arytenoid mucosa
Most common cause of vocal cord paralysis
iatrogenic
Treatment of early stage glottic and supraglottic cancer
Radiation therapy
Treatment of small glottic cancer
partial laryngectomy
Treatment of supraglottic cancer without arytenoid or vocal cord extension
supraglottic laryngectomy
Treatment of advanced laryngeal tumor with extension
total laryngectomy with post op RT
Treatment of subglottic cancer
total laryngectomy
Pattern of spread from primary tumor of oral cavity and lip
I, II, III
Pattern of spread from primary tumor of oropharynx, hypopharynx and larynx
II, III, IV
Pattern of spread from primary tumor of nasopharynx and thyroid
V
Pattern of spread from primary tumor of nasopharynx, soft palate, and lateral and posterior walls of the oropharynx and hypopharynx
Retropharyngeal lymph nodes
Pattern of spread from primary tumor of hypopharynx, cervical esophagus and thyroid
VII
Pattern of spread from advanced tumor of glottis with subglottic spread
delphian node
What is a radical neck dissection or CRILE method
- removal of level I to V lymph nodes
- SCM
- IJV
- Spinal accesory nerve
What is a modified radical neck dissections
- removal of level I to V lymph node
What is a supraomohyoid neck dissection
- removal of level I to III
2. oral cavity malignancy
What is a lateral neck dissection
- removal of level II to IV
2. laryngeal malignancy
What is a posterolateral neck dissection
- removal of II to V
2. thyroid cancer
What is the procedure of choice for thyroglossal duct cyst
Sistrunk procedure
- removal of cyst, tract, and central portion of hyoid bone
- removal of portion of the tongue base up to the foramen cecum
Most common gland involved in salivary gland tumor
parotid gland
most common benign tumor of salivary gland
pleomorphic adenoma
most common malignant tumor of salivary gland
mucoepidermoid carcinoma
Most frequently injured nerve in parotid surgery
greater auricular nerve
- will produce numbness of the lower portion of the auricle and periauricular skin
The syndrome when the auriculotemporal nerve is injured
Frey’s syndrome - postoperative gustatory sweating
What are the nerves at risk in submandibular gland removal
lingual and hypoglossal nerve
What crosses the recurrent laryngeal nerve
inferior thyroid artery
What innervates the cricothyroid muscle
external laryngeal nerve
of the superior laryngeal nerve of the vagus nerve
What is a sensitive marker for medullary thyroid cancer
Serum calcitonin
N: 0 - 4 pg/ml
Treatment of lingual thyroid
- exogenous oral thyroid hormone
- RAI
- hormone replacement
Most common GI symptom of grave’s disease
diarrhea
Absolute contraindication of RAI
- pregnant
2. breastfeeding
Relative contraindication of RAI
- young people
- thyroid nodule
- ophthalmopathy
Treatment of toxic multinodular goiter
subtotal thyroidectomy
Treatment of plummer disease
lobectomy and isthmusectomy
-also known as toxic adenoma
This is a self limiting PAINFUL thyroiditis usually occurs in 30 - 40 y.o women
Subacute Thyroiditis
De quervain’s thyroiditis
Treatment of de quervain’s thyroiditis
NSAID
since it is self limiting
This thyroid disease has a strong association with HLA B35 haplotype
Subacute Thyroiditis
De quervain’s thyroiditis
The most common presentation of this thyroid disease is minimally or moderately enlarged firm granular gland or the awareness of painless anterior neck mass
Hashimoto’s thyroiditis
Chronic Thyroiditis
What is seen in microscopic examination of hashimoto’s thyroiditis?
Hurthle cell or Askanazy cell
This thyroid disease is characterized by replacement of all or part of the thyroid tissue parenchyma by fibrous tissue
Reidel’s thyroiditis
Physical examination reveals a hard woody thyroid gland with fixation to surrounding tissues
Reidel’s thyroiditis
What is the first diagnostice test in a solitary thyroid nodule
FNAB
Most common site of metastasis in papillary thyroid CA
Lungs
What is the type of spread in papillary thyroid CA
lymphatics
What is the most important prognostic factor in determining long term survival of papillary CA
age
Treatment of papillary CA
- < 1.5 cm - lobectomy + isthmusectomy
- multicentric - near total or total thyroidectomy
- with cervical lymph node - MDRD
Most common route of spread of follicular CA
Hematogenous
More common cancer in iodine deficient countries
follicular cancer
Most common site of metastasis in follicular thyroid CA
lung and bone
Treatment of follicular CA
- Follicular lesion - lobectomy + isthmusectomy
- Follicular lesion > 4 cm - total thyroidectomy
- Thyroid cancer - total thyroidectomy
- Positive lymph node - MDRD
Usual site of medullary thyroid cancer
superolateral in the thyroid lobes
Where does medullary thyroid cancer arise from
parafollicular cells
C cells
Disease associated with men 2A
1, pheochromocytoma
2. parathyroid hyperplasia
Disease associated with men 2B
- pheochromocytoma
2. neuroma
Treatment of MTC
Total thyroidectomy with bilateral central node dissection
Most common site of minor salivary gland tumor
junction of hard and soft palate