STIs Flashcards
What is the pathogen causing gonorrhoea?
Neiserria gonorrhoeae
What are the symptoms of gonorrhoea in men?
- asymptomatic 10
- thick profuse yellow discharge
- dysuria
- rectal, pharyngeal infection
What are the symptoms of gonorrhoea in women?
- aymptomatic > 50%
- vaginal discharge
- dysuria
- post-coital/intermenstrual bleeding
What are the complications of gonorrhoea in males?
- epididymitis
- acute monoarthritis
- gonococcal infection
What are the complications of gonorrhoea in women?
- PID
- Bartholin’s abscess
- acute monoarthritis
- gonococcal infection
What are the investigations for gonorrhoea?
- nucleic acid amplification test (NAAT)
- urine/swab vagina/rectum/throat
- gram stain smear
- urethra/cervix.rectum
- swab culture
What is the treatment for gonorrhoea?
- ceftriaxone
- 1g, im
- test at 2 weeks + 3 months
What is the pathogen causing chlamydia?
- chlamydia trachomatis serovars D-K
What are the symptoms of chlamydia in men?
- asymptomatic > 70%
- slight watery discharge
- dysuria
- conjunctivitis
What are the symptoms of chlamydia in women?
- asymptomatic > 80%
- vaginal disharge
- dysuria
- intermenstrual/post-coital bleeding
- conjunctivitis
What are the complications of chlamydia in men?
- epididymitis
- reactive arthritis
- Reiter’s syndrome
What are the complications of chlamydia in women?
- PID -> ectopic pregnancy
- pelvic pain
- infertility
- reactive arthritis
- Reiter’s syndrome
What are the investigations for chlamydia?
- NAAT
- first void urine (men)
- swab cervix/urethra/rectum
What is the treatment for chlamydia?
- doxycycline
- 100mg bd 1 week
- azithromycin (if pregnant)
- 1g po once
- test 3-12 months
What is the pathogen causing herpes?
- herpes cimplex virus 1 + 2
What are the symptoms of herpes?
- aymptomatic 80%
- curning/itching ->blistering -> tender ulceration
- tender inguinal lymphadenopathy
- flu-like symptoms
- dysuria
- neuralgic pain in back, legs, pelvis
What are the complications of herpes?
- autonomic neuropathy (urinary retention)
- neonatal infection
- secondary infection
What are the investigations for herpes?
- clincal diagnosis
- PCR swab from lesion
What is the treatment for herpes?
Primary outbreak:
- aciclover
- lidocaine ointment
Infrequent recurrences:
- lidocaine ointment
- aciclover
Frequent recurrences:
- aciclover long term
What is the pathogen causing trichomoniasis?
- trichomonas vaginalis
What are the symptoms of trichomoniasis?
- usually asymptomatic
- profuse, thin vaginal discharge
What are the complications of trichomoniasis?
- miscarriage
- preterm labour
What are the investigations for trichomoniasis?
- PCR vaginal swab
- microscopy of wet preparation of vaginal discharge
What is the treatment for trichomoniasis?
- metronidazole
What is the pathogen causing anogenital warts?
- HPV 6 + 11
What are the symptoms of anogenital warts?
- lumps- cauliflower texture
- itching
- bleeding
What are the complications of anogenital warts?
- neonatal laryngeal papillomatosis
What are the investigations for anogenital warts?
- clinical diagnosis
- biopsy if unusual
What is the treatment for anogenital warts?
- podophyllotoxin
- imiquimod
- cryotherapy
- diathermy
- scissor removal
What is the pathogen causing syphilis?
- treponema pallidum
What are the symptoms + stages of syphilis?
- primary- local ulcer (chancre)
- secondary- rash, mucosal ulceration, neuro, alopecia
- early latent- asymptomatic (≤ 2 yrs)
- late latent- asymptomatic (≥ 2 yrs)
- tertiary- neuro, CVS, gummatous
What are the complications of syphilis?
- neurosyphilis
- cranial nerve palsies
- cardiac/aortic
- congenital syphilis
What are the investigations for syphilis?
- clinical diagnosis
- serology
- TP, IgGEIA, TPPA, RPR
- PCR on sample from ulcer
What is the treatment for syphilis?
≤ 2 yrs, no neuro:
- benzathine penicillin
- doxycycline
≥ 2 yrs, no neuro:
- benzathine penicillin
- doxycycline
