STIs

Question 1

Neisseria Gonorrhoea infects and causes what?

Answer 1

Infects mucosal surfaces. Causes urethritis in men and endocervicitis in women.

Question 2

What does NG amplify?

Answer 2

HIV.

Question 3

Confrim diagnosis of NG how?

Answer 3

NAA tests on urine, material obtained from sampling is gram stained and cultured on enriched media. Often requires urethral swabs in males and speculum examination in women.

Question 4

NG is resistant to what?

Answer 4

Penicillin, tetracycline and fluoroquines is a major public health problem.

Question 5

Treated with what?

Answer 5

Ceftriaxon 250mgs or ciproflaxin 500mgs.

Question 6

Chlamydia Trachomatis - adapted to exist as what?

Answer 6

Obligate intracellular parasite of eukaryotic cells.

Question 7

What are the 3 serotypes?

Answer 7

• L1,L2,L3 - LGV, cervicitis, prostitis.
• A,B,Ba,C - Ocular Trachoma
• D-K - Oculogenital disease.

Question 8

What can CT cause?

Answer 8

Trachoma, Inclusion conjuctivitis, LGV, urethritis, epididymitis/cervicitis, PID.

Question 9

What can CT cause?

Answer 9

Trachoma, Inclusion conjuctivitis, LGV, urethritis, epididymitis/cervicitis, PID.

Question 10

PID - Pelvic Inflammatory Disease. Symptoms?

Answer 10

Pelvic and abdominal pain, fever, vaginal discharge, cervical tenderness.

Question 11

PID is the leading cause of what?

Answer 11

Infertility and ectopic pregnancy.

Question 12

CT is treated with what?

Answer 12

Doxycycline, 100mgs. Azithromycin 1g stat. Erythromycin 500mgs q.d.s for 7 days.

Question 13

PID is treated with what?

Answer 13

Doxycycline 100mgs for 14 days with metronizadole 400mgs b.d for 5 days and ceftriaxone 250mg b.d.

Question 14

Treponema Pallidum A.K.A?

Answer 14

Syphillis.

Question 15

Diagnosed how?

Answer 15

DFM, Serology and patient with suspected neurosyphillis should have lumbar puncture and CSF exam.

Question 16

How is Treponema pallidum treated?

Answer 16

Early: procaine penicillin - 10 days.
Late: Doxycycline - 28 days. Procaine penicillin 17 days.
Neurosyphillis: Procaine penicillin 17 days and benzylpenicillin 17 days.

Question 17

Describe he 3 classifications of syphilis.

Answer 17

Primary - ulcer and regional lymphadenopathy, incubation 9-90 days.
Secondary - multisystem involvement, appear within 8 weeks of infection. Skin Lesions most common. Anterior uveitis, meningitis, CN palsies and glomerulonephritis.
Tertiary - 30% untreated individuals develop symptomatic late syphilis - neurosyphilis, cardiovascular and gummatous.