STIs Flashcards
Trichimonas: Organism? Hx and Phys? Lab findings? Treatment? Risks?
1) Flagellated Protist 2) Foul smelling, FROTHY greenish discharge; itching and burning; erythema and edema; STRAWBERRY mucosa 3) Cervical smear and wet mount; a) flagellated b) pH>4.5 c) wiff test with KOH 4) Metronidizole (anaerobic bacterial and parasitic infections)–creates radicals 5) Preterm labor
Molluscum: Organism? Spread? Hx? Phys? Lab findings? Treatment? Risks?
1) DNA poxvirus spread through contact (kids; daycare centers) 2) Asymptomatic; pruritis 3) PainLESS lesions around mucosa; DOME-shaped; umbilicated center; flesh color 4) Clinical appearance; Biopsy= intracytoplasmic molluscum bodies with giemsa or wright staining 5) Usually wait for disease to resolve on its own
Scabies: Organism/spread? Hx? Phys? Lab findings? Treatment? Risks?
1) Sarcoptes scabeii- parasite; spread through towels and sheets; CHILDREN; very contagious 2) Itching worse at night; made worse by warm weather 3) Rash–see burrows; maculopapular; see tunneling 4) Mites; bites; feces of mites 5) Permethrin (insecticide)
Syphillus: Organism/spread? Hx? Phys? Lab findings? Treatment? Risks?
1) Trepponema Pallidum– gm- spirochete (also borrelia and leptospira are spirochetes 2) MWM; Prostitutes; highly infectious 3) Prim=painless chancre Secondary=Maculopapular rash on hands and soles of feet; CONDYLOMATA LATA Tertiary= Argyll Robertson pupil; Tabes dorsalis (degeneration of dorsal column) Congenital= Teeth malformation; neuralsensory hearing loss 4) VDRL and confirm with FTA-ABS; Viruses drugs lupus can give false positive 5) Penicillin– desensitize pt.– may have Jarish Herxscheimer rxn
Gonorrhea: Organism/spread? Hx? Phys? Lab findings? Treatment? Risks?
1) Neisseria; gm- diploccocus; mucosal mostly Male to female 2) Yellow mucopurulent discharge 3) PCR to confirm (urine test more accurate in men) 4) Cephalosporin: beta lactam 5) Lead to infertility if not treated (Fitz hugh curtis syndrome– infected liver capsule)
Chlamydia: Organism/spread? Hx? Phys? Lab findings? Treatment? Risks?
1) gm- obligate intracellular; serotype A-L–>GU 2) Asymptomatic until PID; tubuloovary abscess; PURULENT CERVICAL DISCHARGE 3) Urethral swab; DNA and PCR 4) Doxycylin: tetracyclins (30S inhibitors)/ Erythromycin: Macrolide (prevent tRNA elongation–bind 50s subunit)
HIV: Organism/spread? Hx? Phys? Lab findings? Treatment? AIDS diagnosis criteria?
1) RNA Retrovirus 2) Flu like sx; then rash, thrush, weightloss 3) ELISA confirmed with Western Blot 4) HAART Therapy 5) AIDS diagnosed when CD4 is <200
Herpes: Organism/spread? Hx? Phys? Lab findings? Treatment? Risks?
1) HSV; DNA DS 2) Women are more seropositive; vesicular lesions; 3) Seropositivity plus clinical findings 4) Acyclovir: Guanosine analog antiviral 5) HSV-2 leading cause of neonatal encephalitis HSV-1 hangs out in Trigeminal ganglion HSV-2 hangs out in Sacral Ganglion
HepB: Organism/spread? Hx? Phys? Lab findings? Treatment? Risks?
1) DNA virus; icosohedral 2) Mostly asymptomatic; RUQ pain if liver is inflamed; jaundice; fatigue; fever 3) Acute= positive HBsAg or IgM to HBcAg Chronic= HBeAg 4) Interferons of nucleotide analogs
HPV: Organism/spread? Hx? Phys? Lab findings? Treatment? Risks?
1) DNA virus; 16 and 18 are high risk 2) Painful genital nonulcerated lesions; become confluent; nonpurulent discharge 3) Papsmear; viral nuclei acid test or capsid protein test 4) Treat physical findings
Maculopapular rash with burrows
Scabies
Frothy discharge
Trich (flagellated)
DNA poxvirus
Molluscum
Treat with cephalosporin (what is cephalosporin)
Gonorrhea Beta lactam
Painless; domeshaped flesh colored lesions
Molloscum
