Random Drugs

Question 1

What is Fomepizole? MOA?

Answer 1

1) Antidote for methanol and ethylene glycol poisoning
2) blocks alcohol dehydrogenase

Question 2

Drug used for ethylene glycol or methanol poisoining?

Answer 2

Fomepizole (blocks alcohol dehydrogenase)

Question 3

Drug that mimics hangover?

Answer 3

Disulfiram (blocks acetaldehyde dehydrogenase)

Question 4

Antidote for Mercury, Arsenic, or Gold poisoning? (MAG)

Answer 4

Dimercaprol (arsenic poisoning= garlic breath with rice watery stools)

Question 5

Drug to increase excretion of ammonia? 2

Answer 5

Benzoate or phenylbutyrate

Question 6

Ouabin: MOA? Use?

Answer 6

1) Blocks K+ binding site–> inc intracellular Na+ which activates sodium calcium exchanger–>inc calcium–> inc contractility
2) Cardiac glycoside

Question 7

Trimethoprim: MOA? Use?

Answer 7

1) Blocks Dihydrofolate reductase
2) Primarily for UTIs

Question 8

Blocks thymidylate synthase: drug? leads to a build up of?

Answer 8

1) 5- FU
2) dUMP

Question 9

5- FU: MOA?

Answer 9

Blocks thymidylate synthase

Question 10

Blocks ribonucleotide reductase?

Answer 10

Hydroxyurea

Question 11

Hydroxyurea: MOA? use

Answer 11

1) Blocks nucleotide reductase (UDP to dUDP)
2) Sickle cell

Question 12

6MP?

Answer 12

Blocks purine synthesis