stiner- oxygen transport Flashcards

1
Q

The aqueous soln containing formed elements and lacks cells is

A

plasma

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2
Q

what is serum?

A

plasma faction without clotting factors

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3
Q

cellular fraction called what?

A

hematocrit (45%)

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4
Q

function of blood?

A

transport- oxygen, nutrients
distribution- nutrients, removes waste
some components involved in defense- plasma, serum

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5
Q

3 major cell components of blood

A

erythrocytes
leukocytes
thrombocytes

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6
Q

plasma function

A
  • mainly water

- caries albumin, Carbon dioxide, hormones

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7
Q

RBC…derived? functoin

A

red bone marrow
carry oxygen, remove CO2
no organelles or nuclei

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8
Q

WBC function

A

protect the body by fighting diseases

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9
Q

platelets…derived from what? function

A

megakaryocytes

blood coagulation

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10
Q

plasma proteins 2 main catagories

A
  1. proteins synthesized by the liver

2. immunoglobins synthesized by bone marrow

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11
Q

which protein accounts for 50% of plasma proteins

A

albumin

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12
Q

albumin

A

highly polar

responsible for transporting hydrophobic fatty acids, bilirubin, and drugs

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13
Q

Transferrin

A

is a plasma glycoprotein that transports iron through the blood to the liver, spleen, and bone marrow.

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14
Q

Ferritin

A

is the major iron storage protein found in almost all cells of the body.

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15
Q

Hemosiderin

A

is a derivative of ferritin and is found in the liver, spleen, and bone marrow. It is insoluble in aqueous solutions, and forms aggregates that slowly release iron when deficiency occurs.

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16
Q

Ceruloplasmin

A

is the major transport protein for copper, an essential trace element.

17
Q

IgA

A

is found widely in secretions and presents an antiseptic barrier, which protects mucosal surfaces

18
Q

IgD

A

is a surface receptor for antigen in B lymphocytes

19
Q

IgE

A

IgE is present only in trace amounts and acts to bind antigen and promote a release of vasoactive amines from mast cells

20
Q

IgG

A

IgG is the most common immunoglobulin; freely crosses the placenta

21
Q

IgM

A

IgM is confined to the intravascular space and helps eliminate circulating antigens and microorganisms

22
Q

Measurement of _____ concentration in plasma is an essential test in diagnosis and monitoring of infection and sepsis

A

CRP

23
Q

_______ transfer is essential for energy metabolism

A

Oxygen

24
Q

Globins increase the ___________ of the otherwise poorly soluble hydrophobic heme group

A

aqueous solubility

25
Q

complex found in heme

A

porphyin/iron complex

26
Q

75% of iron attached to heme proteins in what state

A

Fe 2+

27
Q

other 15% of iron is where?

A

stored in liver, spleen, bone marrow

28
Q

stored formed of inron is what

A

ferritin, hemosiderin

29
Q

iron predominately reabsorbed where?

A

in the duodenum

30
Q

hemoglobin strucutre

A

Tetrahedral array of 2 identical a-globulins and 2 identical b-globulins
4 heme groups