STI's causing urethritis Flashcards

1
Q

Investigations:

Collection for men?

Collection for women?

Testing:

NAAT - what is it?

A

Urine sample or swab if there is discharge

Self-taken vulvo-vaginal swab
Endocervical swab if speculum inserted

Nucleic acid amplification test - chlamydia and gonorrhoea
A molecular test that detects the genetic material (DNA) of Chlamydia trachomatis.

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2
Q

Chlamydia genital tract infection:

Pathogen

Presentation:

  • Colour of discharge
  • What may they have pain doing? - 2
  • What type of bleeding in women?
A

Chlamydia trachomatis

Clear discharge or just increased vaginal discharge in women

Dysuria
Dyspareunia

PCB
IMB

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3
Q

Chlamydia genital tract infection:

Management - Antibiotics used as:

  • 1st line - A
  • 2nd line - D

What antibiotic is used if they are pregnant?

How far back do you go in contacting partners in women and men?

What should be avoided during Rx?

A

Azithromycin 1g PO witnessed - single dose

Doxycycline 100mg BD for 7 days

Erythromycin 500mg BD

6 months for women
1 month for men

Avoid sex

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4
Q

Chlamydia genital tract infection:

Complications:

  • PID in women - what does this lead to?
  • Fits-Hugh Curtis Syndrome - what is it?
  • What type of bone disease may be triggered by this?

Men:
- Unilateral epididymo-orchitis - what is it?

Obstetrics:

  • What may having chlamydia cause in pregnancy?
A

Tubal damage
Ectopic pregnancies
Infertility

A rare complication of pelvic inflammatory disease (PID) involving liver capsule inflammation leading to the creation of adhesions.

Reactive arthritis (Reiters syndrome)

Inflammation of the epididymis and/or testicle (testis). It is usually due to infection, most commonly from a urine infection or a sexually transmitted infection.

Conjunctivitis
Pneumonia

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5
Q

Gonorrhoea:

Pathogen

This pathogen can infect any columnar epithelium. Where does this happen to allow for swabs to be taken in these areas for testing?

A

Neisseria Gonorrhoeae

Urethra
Endocervix
Rectum
Pharynx

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6
Q

Gonorrhoea:

Men:

  • Discharge - 2 things that may be present?
  • What may the patient have pain doing?
  • Anorectal symptoms - 3

Women:

  • Discharge - 2 things that may be present?
  • What may the patient have pain doing?
  • Anorectal symptom - 1
A

Pus (purulent) and blood

Dysuria

Anal discharge 
Tenesmus 
Procotiits - the lining of inner rectum becomes inflamed 
-----
Pus (purulent) and blood 

Dysuria

Proctitis (directly from anal sex or spread from the vagina)

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7
Q

Gonorrhoea:

Management - Antibiotics used - Single-dose Rx:

  • 1st line - C + A
  • 2nd line - C

What should be avoided during Rx?

A

Ceftriaxone 500mg IM + Azithromycin 1g PO witnessed

Cefixime 400mg PO

Avoid sex

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8
Q

Gonorrhoea:

Local Complications:

Men:
- Unilateral epididymo-orchitis - what is it?
Women:
- A type of vulval abscess they can get?
- Another inflammatory process common in women in their pelvis?

Systemic:

Disseminated gonococcal infection means it spread throughout the body. What could the effects of this be?:

  • Brain
  • Skin
  • Joints
  • Heart

You may also get arthritis-dermatitis syndrome. What is it?

A

Inflammation of the epididymis and/or testicle (testis). It is usually due to infection, most commonly from a urine infection or a sexually transmitted infection.

Bartholinitis (abscess)
PID

Meningitis
Pustular rash
Septic arthritis
Infective endocarditis

A form of DGI that usually comprises a triad of manifestations which include tenosynovitis, dermatitis, and polyarthralgia. It is also often associated with constitutional symptoms such as fever, chills, and body malaise.

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9
Q

Gonorrhoea:

Neonatal complications:

  • Eyes
  • Lungs
  • Rectum

What is a rising complication of G which would hinder Rx?

A

Conjunctivitis

Pneumonia

Rectal infection

AB resistance

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10
Q

What is the difference between Gonorrhoea and NSU?

A

Non-specific urethritis (NSU) means any inflammation of a MAN’s urethra (the tube that carries urine from the bladder to the outside) that is not caused by gonorrhoea (a sexually transmissible infection).

It is sometimes called non-gonococcal urethritis (NGU).

Several organisms can cause NSU but, in many cases, the specific organism can’t be identified.

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