Case 14 Basics Flashcards
Functions of oestrogen:
Fertility - 3
Lactation - 2
Secondary sexual characteristics - 3
Growth of follicles
Endometrial growth
Increased tubal motility and uterine contractions
Duct growth
Inhibits milk production
Breast development Female habitus (e.g. skin) Development of external genitalia
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Functions of progesterone:
Fertility - 3
Lactation - 2
Endometrial receptivity
Reduced tube motility
Reduced uterine contractions
Stimulates lobuloalveolar development
Inhibits milk letdown
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DO QUIZ ON THE MENSTRUAL CYCLE
https://geekymedics.com/menstrual-cycle-quiz/
What hormone stops FSH production in a negative feedback loop?
Inhibin
FSH and LH stimulate inhibin production then the negative feedback
3 feedback stages in the menstrual cycle:
What hormone causes an LH surge?
What hormones stop LH production?
How does a drop in P and O start the cycle again?
At what point of a 28 day menstrual cycle is it best to get pregnant?
Increased oestrogen
Increased P and O
The brain thinks everything has stopped - GnRH production increases
12-14 days
Define:
Primary amenorrhoea - 2 definitions
Secondary amenorrhoea
Menses not started after 14 yrs with no sexual characteristics
Absence of menses if they’ve had 3-6 consecutive months of periods
Put the following sexual characteristics in order of development:
Axillary hair
Menses begins
Growth of pubic hair
Breast buds
Breast bud > growth of pubic hair > axillary hair > menarche
Puberty:
Average age
What can cause you to go into puberty earlier?
At what 2 ages should the girl be investigated?
12.7 years
If no periods by 16 or no signs of puberty by 14
Issue of having polymenorrhoea?
May become anaemia - Low iron - prescribe iron
What can cause early menarche?
Being overweight - high BMI
Effects of low BMI on periods?
Loss of GnRH due to stress
Turns whole system off
e.g. anorexia
Effects of high BMI on periods?
High levels of oestrogen
Altered feedback
Continous high level means LH surge doesn’t happen at right time - look up
