STI's Flashcards
Chlamydia organism
Chlamydia trachomatis
Diagnosis of chlamydia
NAAT - nucleic acid amplification test
First pass urine in men
Vulvovaginal swabs in women
When is the ideal time to carry out chlamydia testing
2 weeks after a possible exposure
Microscopy showing red inclusion bodies are typical of which infection
Chlamydia
Management of chlamydia
Azithromycin 1g single oral dose OR
Doxycycline 100mg PO BD for 7 days OR
Erythromycin 500mg PO BD for 14 days
What is Fitz-Hugh-Curtis syndrome
A rare complication of pelvic inflammatory disease (PID) involving liver capsule inflammation leading to the creation of adhesions.
What is lymphogranuloma venereum and what are the symptoms of it
An infection caused by a more invasive serotype of chlamydia trachomatis which causes a triad of inguinal lymphadenopathy, proctocolitis and fever
In England what ages is the national chlamydia screening programme open to
Age 15-24
Organism that causes gonorrhea
Neisseria gonorrhoeae (gram negative diplococci)
Diagnosis of gonorrhea
NAAT - nucleic acid amplification test
First pass urine in men
Vulvovaginal swabs in women
Urethral/cervical/anal/oral swabs taken for culture prior to administering antibiotics to assess sensitivities
Management of gonorrhea
Ceftriaxone 500mg IM injection single dose AND Azithromycin 1g oral single dose
How long after gonorrhea treatment do you test again as a test of cure
2 weeks
Organism that causes syphilis
Treponema pallidum
What are the 5 stages of syphilis
Primary Secondary Early latent Late latent Tertiary
What is the primary stage of syphilis infection characterised by
Development of an indurated painless ulcer called a chancre most often on the genitals
What is the secondary stage of syphilis infection characterised by
6 weeks to 6 months following the primary infection a widespread non-pruritic maculopapular rash involving the trunk, palms and soles develops accompanied by alopecia, condylomata lata (painless, warty lesions on the genitalia), generalised lymphadenopathy, oral snail-track lesions and constitutional symptoms (pyrexia, fatigue, malaise).
Features of tertiary syphilis
Neurosyphilis – Tabes dorsalis (dorsal column demyelination), general paresis, strokes, Argyll-Robertson pupil (bilaterally small pupils that accommodate but don’t constrict directly to light)
Cardiovascular syphilis – Aortitis, aortic aneurysms
Gummatous syphilis – Formation of granulomas on bone, skin and mucosa
Features of congenital syphilis
Blunted upper incisor teeth (Hutchinson’s teeth)
Rhagades (linear scars at the angle of the mouth)
Saber shins (anterior bowing of the tibia)
Saddle nose
Deafness
Keratitis
Management of syphilis
Benzathine benzylpenicillin 1.8g IM single dose AND Prednisolone 60mg PO OD for 3 days (give for 24hrs before the IM injection)
Which herpes virus is spread via the oral route
HSV 1
Which herpes virus is spread via the genital route
HSV 2
Diagnosis of herpes
HSV PCR or culture from swabs taken from lesions- when taking the sample remember to burst the lesion and swab the fluid/base of the ulcer.
Management for the primary episode of genital herpes
Aciclovir 400mg PO TDS for 7-10 days
Management for recurrent episodes of genital herpes
Aciclovir 800mg PO TDS for 2 days
Ideally, within how many days from symptom onset should you give Aciclovir in the primary episode of genital herpes infection
Within 3 days
Which viruses cause genital warts
HPV 6 and 11
First line management of genital warts
Topical podophyllotoxin
Topical imiquimod
Second line management of genital warts
Cryotherapy
Surgical excision
Type of vaginal discharge caused by TV
Thin, frothy
Yellow-green
Fishy smell
Diagnosis of TV
Alkaline vaginal pH
High vaginal swab for microscopy, culture of discharge
In men - urethral swab or first pass urine
Treatment for TV infection
Metronidazole 2g oral as single dose
