Steroids and Glucocorticoids Flashcards
What is cortisol and how does it effect the body?
Cortisol is a steroid hormone released from adrenal glands. The hormone is released during periods of stress on the body which activates the sympathetic pathway. It increases your heart rate and blood pressure.
When released, insulin sensitivity is reduced, glucose uptake from tissue is reduced and glycogenesis is increased which all leads to hyperglycaemia.
what is a glucocorticoid?
An anti-inflammatory steroid hormone used in the treatment of inflammatory conditions and auto-immune diseases.
types of steroid therapy
Topical
Oral
Intravenous
Inhaled
Cavity injection eg. joints
types of steroid therapy
Topical
Oral
Intravenous
Inhaled
Cavity injection eg. joints
Hydrocortisone properties
Low potency
Used in topical creams
Natural glucocorticoid
Calms down inflammation
What is an immunomodulator?
Drug which alters the immune response in a beneficial way for a patient.
What is an interferon?
A natural anti-viral and type of immunomodulator
Effects of steroids on the eye
Increased IOP which can cause glaucoma if sustained over long period of time. PSSC when taken systemically eg. intravenous. Macular oedema and central serous retinopathy.
