Drugs with ocular effects

Question 1

What is amiodarone used for and what ocular side effects can it have? (3 ocular effects)

Answer 1

Heart arrhythmias. It can cause vortex keratopathy, anterior lens deposits and optic neuropathy.

Question 2

What is the indicated use for hydroxychloroquine and ocular effects?

Answer 2

Rheumatoid arthritis, lupus or prophylactic use for malaria. Side effects include, vortex keratopathy, toxic maculopathy, pigmentary changes in retina.

Question 3

Tamoxifen - use and ocular side effects.

Answer 3

An anti-oestrogen drug used for oestrogen receptor positive breast cancer and infertility treatment. It can have effects such as; vortex keratophathy, toxic maculopathy, crystalline deposits.

Question 4

Chlorpromazine - Ocular effects and uses.

Answer 4

used to treat schizophrenia, depression, and anxiety. ocular effects include; corneal stromal and endothelial deposits, pigment deposits in conjunctiva, stellate cataract, nystagmus, abnormal EOM motility. As is can act as an anti-cholinergic, effects which Concorde with these drugs like mydriasis, reduced lacrimal secretion and increased IOP can be seen.

Question 5

Isotretinoin used for and ocular effects

Answer 5

Ance. Its ocular effects include opacities in cornea, keratitis, conjunctivitis, optic neuritis.

Question 6

Tetracyclines - mine and doxy side effects and indication for usage.

Answer 6

Used to treat acne, rosacea, infections, limes disease. It can have ocular effects such as; conjunctival inclusion cysts and optic nerve oedema.

Question 7

Carbamazepine uses and ocular side effects

Answer 7

Used for epilepsy and neuralgia. Its ocular effects include; conjunctival inclusion cysts, pigment deposits in conjunctiva, abnormal EOM motility and nystagmus.

Question 8

Corticosteroids - Prednisone, dexamethasone and hydrocortisone uses and ocular effects.

Answer 8

Used for inflammation, auto-immune diseases, asthma and CPOD. Ocular effects include; increased IOP and reduced drainage, posterior sub capsular cataract (PSSC), macular oedema.

Question 9

Topiramate uses and ocular effects.

Answer 9

Seizures and migraines. Ocular effects include; ciliary body oedema, anterior shift of iris and lens, angle closure and increased IOP.

Question 10

Fingolimod - uses and ocular effects

Answer 10

Used for MS. Ocular effects - macula oedema

Question 11

Vigabatrin uses and ocular effects

Answer 11

For epilepsy. Ocular effects - Optic neuropathy with VF loss

Question 12

Tamsulosin ocular effects and indication for usage.

Answer 12

Used for benign prostatic hyperplasia and its ocular effects include; floppy iris syndrome and poor pupil dilation due to decrease in dilator muscle tone.