Steroids and Adrenal Hormones Structure Flashcards
1
Q
A
Aldosterone
Mineral Agonist
Aldosterone
2
Q
A
Fludrocortisone Acetate
Mineralcorticoid Agonist
(main activity)
Prodrug Oral
3
Q
A
Mineralcorticoid Antagonist
Oral
4
Q
A
M Antagonist
Oral
5
Q
A
G agonist
Cortisol
Oral
6
Q
A
G Agonist
(not active topically, know how to activate topically)
prodrug
7
Q
A
G Agonist
Prodrug
8
Q
A
G agonist
9
Q
A
G Agonist
10
Q
A
G Agonist
11
Q
A
G agonist
12
Q
A
G Agonist
13
Q
A
G Agonist
14
Q
A
G agonist
15
Q
A
G Agonist
16
Q
A
G Agonist
Prodrug
17
Q
A
G Agonist
18
Q
A
G Antagonist at high doses
Progesterone Antagonist at low doses as abortifacient
Oral
19
Q
A
Cholesterol
(precursor to steroid hormones)
20
Q
A
Progestin
Progesterone
21
Q
A
Androgen
Testosterone
22
Q
A
G
Cortisol
23
Q
A
M
Aldosterone
24
Q
A
Estrogen
Estradiol
25
Estrogen Agonist
Estrone (E1)
26
Estrogen Agonist
Estriol (E3)
27
Estrogen Metabolite
Agonist
28
Estradiol Metabolite Agonist
| (prodrug)
29
Estradiol Metabolite Agonist
| (prodrug)
30
Conjugated Estrogen Metabolite Agonist
| (oral, prodrug)
31
Conjusated Estrogen Metabolite Agonist
| (Oral, prodrug)
32
Conjugated Estrogen Metabolite Agonist
| (oral, prodrug)
33
Conjugated Estrogen Metabolite Agonist
| (oral, prodrug)
34
Conjugated Estrogen Metabolite Agonist
| (oral, prodrug)
35
Conjugated Estrogen Metabolite Agonist
| (oral, Prodrug)
36
Conjugated Estrogen Metabolite Agonist
| (oral, Prodrug)
37
Conjugated Estrogen Metabolite Agonist
| (oral, prodrug)
38
Synthetic Strogen Agonist
| (IM, prodrug, long DOA)
39
Synthetic Estrogen Agonist
| (IM, prodrug, long Doa)
40
Synthetic Estrogen Agonist (oral)
Ethinyl estradiol
Main component of birth control pills
41
Synthetic Estrogen Agonist (oral, prodrug)
42
Synthetic Estrogen Agonist (oral, prodrug)
43
Non-steroidal Estrogen Agonist
44
Phytoestrogen
Estrogen Agonist
(oral)
45
Phytoestrogen
Estrogen Agonist
(oral)
46
Phytoestrogen
Estrogen Agonist
(oral)
47
SERM / Antiestrogen / Estrogen Antagonist
Mixed agonist, antag Nonsteroidal, Prodrug
(oral)
Use: chemoprevention & treatment of breast cancer
48
Antiestrogen / Estrogen Antagonist Mixed agonist, antag Nonsteroidal, Prodrug
(oral)
Use: Breast cancer
49
Antiestrogen / ER Antagonist Mixed agonist, antag Nonsteroidal, Prodrug (oral)
Use: induces ovulation
50
Antiestrogen / Estrogen Antagonist Pure antagonist
Steroidal
(IM)
51
SERM or Antiestrogen Estrogen Antagonist
(oral)
Use: osteoporosis & chemoprevention of breast cancer in women with osteoporosis
52
Antiestrogen
Pure Estrogen Antagonist (prodrug)
53
Antiestrogen
Pure Estrogen Antagonist (prodrug)
54
Competitive Steroidal Aromatase Inhibitor
55
Competitive Nonsteroidal Aromatase Inhibitor
| (oral)
56
Competitive Nonsteroidal Aromatase Inhibitor
| (oral)
57
SERM / Antiestrogen
Mixed estrogen agonist/antag
Nonsteroidal, Prodrug
(oral)
58
SERM / Antiestrogen
Mixed estrogen agonist/antagonist Nonsteroidal
(oral)
Use: prevention of osteroporosis Treatment of menopausal symptoms in combo w/ conj E
59
Progestin Agonist
Progesterone
(draw it)
60
Progestin Metabolite
(inactive)
61
Progestin Agonist
| (IM)
62
Progestin Agonist
| (IM, oral)
63
Progestin Agonist
| (oral)
64
Weak Progestin Agonist & Weak Androgen Agonist
(Testosterone derivative)
65
Progestin Agonist (Testosterone derivative)
66
Progestin Agonist (Testosterone derivative)
67
Progestin Agonist (19-Nortestosterone derivative)
(oral)
68
Progestin Agonist
(19-Nortestosterone derivative)
(oral, prodrug)
69
Progestin Agonist
(19-Nortestosterone derivative)
(oral, prodrug)
70
Progestin Agonist
(19-Nortestosterone derivative)
(oral)
Also used as emergency contraceptive
71
Progestin Agonist
(19-Nortestosterone derivative)
(oral, prodrug)
(metabolite also active)
72
Progestin Agonist
(19-Nortestosterone derivative)
(oral)
73
Progestin Agonist
(19-Nortestosterone derivative)
(transdermal, metabolite also active)
74
Progestin Agonist
(19-Nortestosterone derivative)
(oral, prodrug)
75
Progestin Agonist
(19-Nortestosterone derivative)
(vaginal)
76
Progestin Agonist
(19-Nortestosterone derivative)
(oral, prodrug)
77
Progestin Agonist
(oral)
(look at similarity to MR Antag)
78
Progestin Antagonist, Antiprogestin Abortifacient
Glucocorticoid Antagonist, Antiglucocorticoid
(oral)
79
Prostaglandin
Abortifacient
(oral)
80
Prostaglandin
Abortifacient
(oral)
81
Prostaglandin
Abortifacient
(oral)
82
Selective PR Modulator Progestin Antagonist, Antiprogestin Progestin Agonist
Used as Emergency Contraceptive
(oral)
83
Progestin Agonist
| (oral)
84
