Steroids and Adrenal Hormones Structure Flashcards

1
Q
A

Aldosterone

Mineral Agonist

Aldosterone

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2
Q
A

Fludrocortisone Acetate

Mineralcorticoid Agonist

(main activity)

Prodrug Oral

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3
Q
A

Mineralcorticoid Antagonist

Oral

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4
Q
A

M Antagonist

Oral

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5
Q
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G agonist

Cortisol

Oral

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6
Q
A

G Agonist

(not active topically, know how to activate topically)

prodrug

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7
Q
A

G Agonist

Prodrug

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8
Q
A

G agonist

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9
Q
A

G Agonist

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10
Q
A

G Agonist

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11
Q
A

G agonist

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12
Q
A

G Agonist

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13
Q
A

G Agonist

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14
Q
A

G agonist

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15
Q
A

G Agonist

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16
Q
A

G Agonist

Prodrug

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17
Q
A

G Agonist

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18
Q
A

G Antagonist at high doses

Progesterone Antagonist at low doses as abortifacient

Oral

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19
Q
A

Cholesterol

(precursor to steroid hormones)

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20
Q
A

Progestin

Progesterone

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21
Q
A

Androgen

Testosterone

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22
Q
A

G

Cortisol

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23
Q
A

M

Aldosterone

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24
Q
A

Estrogen

Estradiol

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25
Q
A

Estrogen Agonist

Estrone (E1)

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26
Q
A

Estrogen Agonist

Estriol (E3)

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27
Q
A

Estrogen Metabolite

Agonist

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28
Q
A

Estradiol Metabolite Agonist

(prodrug)

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29
Q
A

Estradiol Metabolite Agonist

(prodrug)

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30
Q
A

Conjugated Estrogen Metabolite Agonist

(oral, prodrug)

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31
Q
A

Conjusated Estrogen Metabolite Agonist

(Oral, prodrug)

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32
Q
A

Conjugated Estrogen Metabolite Agonist

(oral, prodrug)

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33
Q
A

Conjugated Estrogen Metabolite Agonist

(oral, prodrug)

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34
Q
A

Conjugated Estrogen Metabolite Agonist

(oral, prodrug)

35
Q
A

Conjugated Estrogen Metabolite Agonist

(oral, Prodrug)

36
Q
A

Conjugated Estrogen Metabolite Agonist

(oral, Prodrug)

37
Q
A

Conjugated Estrogen Metabolite Agonist

(oral, prodrug)

38
Q
A

Synthetic Strogen Agonist

(IM, prodrug, long DOA)

39
Q
A

Synthetic Estrogen Agonist

(IM, prodrug, long Doa)

40
Q
A

Synthetic Estrogen Agonist (oral)
Ethinyl estradiol
Main component of birth control pills

41
Q
A

Synthetic Estrogen Agonist (oral, prodrug)

42
Q
A

Synthetic Estrogen Agonist (oral, prodrug)

43
Q
A

Non-steroidal Estrogen Agonist

44
Q
A

Phytoestrogen

Estrogen Agonist

(oral)

45
Q
A

Phytoestrogen

Estrogen Agonist

(oral)

46
Q
A

Phytoestrogen

Estrogen Agonist

(oral)

47
Q
A

SERM / Antiestrogen / Estrogen Antagonist
Mixed agonist, antag Nonsteroidal, Prodrug
(oral)
Use: chemoprevention & treatment of breast cancer

48
Q
A

Antiestrogen / Estrogen Antagonist Mixed agonist, antag Nonsteroidal, Prodrug
(oral)
Use: Breast cancer

49
Q
A

Antiestrogen / ER Antagonist Mixed agonist, antag Nonsteroidal, Prodrug (oral)
Use: induces ovulation

50
Q
A

Antiestrogen / Estrogen Antagonist Pure antagonist
Steroidal
(IM)

51
Q
A

SERM or Antiestrogen Estrogen Antagonist
(oral)
Use: osteoporosis & chemoprevention of breast cancer in women with osteoporosis

52
Q
A

Antiestrogen
Pure Estrogen Antagonist (prodrug)

53
Q
A

Antiestrogen
Pure Estrogen Antagonist (prodrug)

54
Q
A

Competitive Steroidal Aromatase Inhibitor

55
Q
A

Competitive Nonsteroidal Aromatase Inhibitor

(oral)

56
Q
A

Competitive Nonsteroidal Aromatase Inhibitor

(oral)

57
Q
A

SERM / Antiestrogen

Mixed estrogen agonist/antag

Nonsteroidal, Prodrug

(oral)

58
Q
A

SERM / Antiestrogen
Mixed estrogen agonist/antagonist Nonsteroidal
(oral)
Use: prevention of osteroporosis Treatment of menopausal symptoms in combo w/ conj E

59
Q
A

Progestin Agonist

Progesterone

(draw it)

60
Q
A

Progestin Metabolite

(inactive)

61
Q
A

Progestin Agonist

(IM)

62
Q
A

Progestin Agonist

(IM, oral)

63
Q
A

Progestin Agonist

(oral)

64
Q
A

Weak Progestin Agonist & Weak Androgen Agonist

(Testosterone derivative)

65
Q
A

Progestin Agonist (Testosterone derivative)

66
Q
A

Progestin Agonist (Testosterone derivative)

67
Q
A

Progestin Agonist (19-Nortestosterone derivative)

(oral)

68
Q
A

Progestin Agonist

(19-Nortestosterone derivative)

(oral, prodrug)

69
Q
A

Progestin Agonist

(19-Nortestosterone derivative)

(oral, prodrug)

70
Q
A

Progestin Agonist

(19-Nortestosterone derivative)

(oral)

Also used as emergency contraceptive

71
Q
A

Progestin Agonist

(19-Nortestosterone derivative)

(oral, prodrug)

(metabolite also active)

72
Q
A

Progestin Agonist

(19-Nortestosterone derivative)

(oral)

73
Q
A

Progestin Agonist

(19-Nortestosterone derivative)

(transdermal, metabolite also active)

74
Q
A

Progestin Agonist

(19-Nortestosterone derivative)

(oral, prodrug)

75
Q
A

Progestin Agonist

(19-Nortestosterone derivative)

(vaginal)

76
Q
A

Progestin Agonist

(19-Nortestosterone derivative)

(oral, prodrug)

77
Q
A

Progestin Agonist
(oral)
(look at similarity to MR Antag)

78
Q
A

Progestin Antagonist, Antiprogestin Abortifacient

Glucocorticoid Antagonist, Antiglucocorticoid

(oral)

79
Q
A

Prostaglandin

Abortifacient

(oral)

80
Q
A

Prostaglandin

Abortifacient

(oral)

81
Q
A

Prostaglandin

Abortifacient

(oral)

82
Q
A

Selective PR Modulator Progestin Antagonist, Antiprogestin Progestin Agonist
Used as Emergency Contraceptive

(oral)

83
Q
A

Progestin Agonist

(oral)

84
Q
A