Stereochemistry

Question 1

Isomerism:

Answer 1

Constitutional Isomers and
Stereoisomers

Question 2

Stereoisomers are isomers…

Answer 2

with the same
molecular formula and same connectivity of
atoms but different arrangement of atoms in
space

Question 3

Sub divisions of isomers

Answer 3

-Isomers

-Constitutional isomers

-Stereoisomers

-Enantiomers

-Diastereomers

Question 4

Isomers:

Answer 4

Different compounds with same molecular formula

Question 5

Constitutional isomers:

Answer 5

Isomers whose atoms have a different connectivity

Question 6

Stereoisomers:

Answer 6

Isomers that have the same connectivity but that differ in the arrangement of their atoms in space

Question 7

Enantiomers:

Answer 7

stereoisomers whose molecules
are nonsuperposable mirror images

Question 8

Diastereomers:

Answer 8

stereoisomers whose
molecules are not mirror images of each other

Example: cis and trans double bond isomers, cis and trans cycloalkane isomers

Question 9

Chiral molecule:

Answer 9

-Not superimposable on its mirror image

-Can exist as a pair of enantiomers

Question 10

Pair of enantiomers:

Answer 10

• A chiral molecule and its mirror image

Question 11

Achiral molecule

Answer 11

• Superimposable on its mirror image

Question 12

The Biological Importance of Chirality:

Answer 12

The binding specificity of a chiral receptor site
for a chiral molecule is usually only favorable in
one way

Question 13

Fischer Projection Formulas

Answer 13

A 2-dimensional representation of chiral molecules

• Vertical lines represent bonds that project behind the
  plane of the paper

-Horizontal lines represent bonds that project out of the
plane of the paper