Steps of Muscle Twitch Flashcards

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1
Q

3 Periods of Muscle Contraction

A

Latent, contraction, relaxation

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2
Q

1.

A

Somatic motor neuron action potential

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3
Q

2.

A

Voltage-gated Ca2+ channels open

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4
Q

3.

A

Ca2+ induces vesicle exocytosis

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5
Q

4.

A

ACh released in synapse (NMJ)

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6
Q

5.

A

ACh binds to motor end plate nicotinic receptors

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7
Q

6.

A

Muscle cell depolarizes

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8
Q

7.

A

Action potential travels along sarcolemma

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9
Q

8.

A

Action potential travels spread down t-tubles

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10
Q

9.

A

DHP channels change shape

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11
Q

10.

A

RyR channels in SR open

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12
Q

11.

A

Ca2+ enters sarcoplasm

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13
Q

12.

A

Ca2+ bind to troponin

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14
Q

13.

A

Tropomyosin is shifted off of binding sites

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15
Q

Steps 1-13

A

Latent Period

Between motor neuron AP and force

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16
Q

14.

A

Myosin heads attach to actin

17
Q

15.

A

Myosin uses ATP to bend at hinge

18
Q

16.

A

Actin pulled towards M-line

19
Q

17.

A

Sarcomere shortens

20
Q

Steps 14-17

A

Contraction period

Force being produced

21
Q

18.

A

RyR channels close + ACh broken down in NMJ

22
Q

19.

A

Ca2+ actively pumped into SR

23
Q

20.

A

Ca2+ pops off of troponin

24
Q

21.

A

Tropomyosin re-covers binding sites on actin

25
Q

22.

A

Sarcomere returns to resting length due to elasticity

26
Q

Step 18-22

A

Relaxation period

Force reducing