Step 1 ANS drugs Flashcards
bethanechol uses
postoperative/neurogenic ileus, urinary retention
bethanechol mechanism
cholinomimetic
carbachol uses
glaucoma, pupillary contraction, IOP relief
carbachol mechanism
direct cholinomimetic
pilocarpine mechanism
direct cholinomimetic
pilocarpine uses
glaucoma (in emergencies, especially narrow angle), potent stimulator of sweat, tears, saliva
methacholine mechanism
direct cholinomimetic
methacholine use
challenge test for asthma
neostigime mechanism
cholinesterase inhibitor
neostigime uses
myasthenia gravis, postoperative blockade reversal, urinary retention
pyridostigime mechanism
cholinesterase inhibitor
pyridostigmine uses
myasthenia gravis (doesn’t penetrate CNS)
edrophonium mechanism
cholinesterase inhibitor
edrophonium use
short acting, diagnosis of MG
physostigime uses
glaucoma, atropine overdose
physostimine mechanism
cholinesterase inhibitor
echothiophate mechanism
cholinesterase inhibitor
echolthiophate use
glaucoma
cholinomimetic toxicity
brochospasm (exacerbate COPD, asthma), peptic ulcers
antidote to cholinesterase poisoning
atropine and pralidoxime
tropicamide use
eye dilation
muscarinic antagonists
atropine, homatropine, tropicamide, scopolamine, ipratropium, oxybutynin, glycopurrolate, methscopolamine, pirenzepine, propantheline
scopolamine use
motion sickness
ipratropium use
asthma, COPD