Stem Cells

Question 1

Totipotent Stem Cell

Answer 1

A type of stem cell that can differentiate into any kind of cell, including the outer layer of the placenta. Present in the early embryo-8 cell stage.

Question 2

Pluripotent Stem Cell

Answer 2

A type of stem cell that can differentiate into any kind of cell, except those associated with the outer layer of the placenta. Present from the 8 cell stage - 5 day mark; in the blastocyst.

Question 3

Multipotent Stem Cell

Answer 3

A differentiated cell that can give rise to multiple, yet limited cell types. There is no going back, creates specialized cell types.

Question 4

Stem Cells

Answer 4

Are what give rise to all the cells in the body, and have the ability to self-renew.

Question 5

Ectoderm

Answer 5

Associated with neural

Question 6

Mesoderm

Answer 6

Associated with blood and bone

Question 7

Endoderm

Answer 7

Associated with liver and kidneys

Question 8

Induced Pluripotent Stem Cells

Answer 8

Could take adult stem cells and treat them chemically to create pluripotent stem cells from multipotent cells. Multipotent cells can be taken from any tissue, or blood.

Question 9

Difference between iPSC and hESC

Answer 9

Not significant in some cases, however gene expression signature is different, iPSC has a lower expression than hESC. Unknown if clinically relevant.