STDs Flashcards
Routes of HSV transmission
Sexually
Perinatally
Which HSV is most prevalent?
HSV-2
How long can HSV remain in latency stage?
Indefinitely
Route of admin for HSV
Systemic antivirals (PO) Topical NOT recommended
Tx for first clinical episode of HSV
Acyclovir
Famciclovir
Valacyclovir
Recommendations for suppressive HSV tx
Acyclovir
Famciclovir
Valacyclovir
How to initiate episodic HSV tx
Within 1 day will shorten dur of lesions
Acyclovir
Famciclovir
Valacyclovir
Most frequently reported disease in US
Chlamydia
1 Risk Factor for Chlamydia
Adolescence New/multiple sex partners History/Presence of STD infection Oral contraceptive user Lack of barrier contraceptive
Transmission of chlamydia
Sexual and vertical
Chlamydia infects ______ cells
Columnar epithelial
Two forms present in chlamydia life cycle
Elementary Body (EB) Reticulate Body (RB)
Species of chlamydia
C. Trachomatis
Clinical complications of chlamydia
Conjunctivitis Urethritis Proctitis Cervicitis Rhinitis Epididymitis (swollen testicles) Endometritis Acute salpingitis
Gold standard for chlamydia testing
Culture
Test for multiple STDs
NAATs (chlamydia, gonorrhea, and trichimonas)
Tx for uncomplicated chlamydia
Azithromycin
Doxycycline
Alternatives - erythromycin, ofloxacin, levofloxacin
Most common ADE with azithromycin
GI effects
Azithromycin drug class
Macrolide
Screening for chlamydia in women
Mostly asymptomatic
Decreases birth defects and PID
Reportable STDs
Chlamydia
Gonorrhea
Syphilis
Tx of gonorrhea in pharynx, cervix, urethra, and rectum
Ceftriaxone (or cefixime)
PLUS
Azithromycin or Doxycycline
Test for cure with chlamydia
Not recommended unless symptomatic or pregnant
Test for cure with gonorrhea
Not recommended if DOC used.
Recommended if alternative tx used.
HPV high risk genotypes
16 & 18
HPV low risk genotypes
6 & 11
Tx of HPV genital warts (Patient applied)
PODOFILOX sol or gel
or
Imiquimod cream
Sinecatechins ointment
Tx of HPV genital warts (Dr. Applied)
Cryotherapy
Surgery
HPV Vax
Two types
Bivalent vax (HPV2)
Quadrivalent (HPV4)
Given as early as 11 years old
Dosing for HPV Vax
3 doses over 6 mo period
STDs associated with PID
Chlamydia and gonorrhea
Most common pathogens with PID
Gonorrhea and chlamydia
Tx for PID
tx of gonorrhea and chlamydia
Ceftriaxone plus Doxycycline w or wo metronidazole
Azithromycin (doxy if not tolerated)
If pen allergy - larger dose Azithromycin
PID tx regimens should cover…
N.gonorrhea C.trachomatis Anaerobes Gram - Streptococci
Syphilis transmission routes
Sexual
Vertical
Syphilis etiologic agent
Treponema pallidum
DOC for syphilis
Benzathine Pen G IM single dose
Alternatives:
Doxy
Tetracycline
Tx for trichimonas
Metronidazole
Tinidazole
