STDs

Question 0

Routes of HSV transmission

Answer 0

Sexually

Perinatally

Question 1

Which HSV is most prevalent?

Answer 1

HSV-2

Question 2

How long can HSV remain in latency stage?

Answer 2

Indefinitely

Question 3

Route of admin for HSV

Answer 3

Systemic antivirals (PO)
Topical NOT recommended

Question 4

Tx for first clinical episode of HSV

Answer 4

Acyclovir
Famciclovir
Valacyclovir

Question 5

Recommendations for suppressive HSV tx

Answer 5

Acyclovir
Famciclovir
Valacyclovir

Question 6

How to initiate episodic HSV tx

Answer 6

Within 1 day will shorten dur of lesions
Acyclovir
Famciclovir
Valacyclovir

Question 7

Most frequently reported disease in US

Answer 7

Chlamydia

Question 8

1 Risk Factor for Chlamydia

Answer 8

Adolescence 
New/multiple sex partners
History/Presence of STD infection
Oral contraceptive user
Lack of barrier contraceptive

Question 9

Transmission of chlamydia

Answer 9

Sexual and vertical

Question 10

Chlamydia infects ______ cells

Answer 10

Columnar epithelial

Question 11

Two forms present in chlamydia life cycle

Answer 11

Elementary Body (EB)
Reticulate Body (RB)

Question 12

Species of chlamydia

Answer 12

C. Trachomatis

Question 13

Clinical complications of chlamydia

Answer 13

Conjunctivitis 
Urethritis 
Proctitis 
Cervicitis
Rhinitis
Epididymitis (swollen testicles)
Endometritis
Acute salpingitis

Question 14

Gold standard for chlamydia testing

Answer 14

Culture

Question 15

Test for multiple STDs

Answer 15

NAATs (chlamydia, gonorrhea, and trichimonas)

Question 16

Tx for uncomplicated chlamydia

Answer 16

Azithromycin
Doxycycline
Alternatives - erythromycin, ofloxacin, levofloxacin

Question 17

Most common ADE with azithromycin

Answer 17

GI effects

Question 18

Azithromycin drug class

Answer 18

Macrolide

Question 19

Screening for chlamydia in women

Answer 19

Mostly asymptomatic

Decreases birth defects and PID

Question 20

Reportable STDs

Answer 20

Chlamydia
Gonorrhea
Syphilis

Question 21

Tx of gonorrhea in pharynx, cervix, urethra, and rectum

Answer 21

Ceftriaxone (or cefixime)
PLUS
Azithromycin or Doxycycline

Question 22

Test for cure with chlamydia

Answer 22

Not recommended unless symptomatic or pregnant

Question 23

Test for cure with gonorrhea

Answer 23

Not recommended if DOC used.

Recommended if alternative tx used.

Question 24

HPV high risk genotypes

Answer 24

16 & 18

Question 25

HPV low risk genotypes

Answer 25

6 & 11

Question 26

Tx of HPV genital warts (Patient applied)

Answer 26

PODOFILOX sol or gel or Imiquimod cream Sinecatechins ointment

Question 27

Tx of HPV genital warts (Dr. Applied)

Answer 27

Cryotherapy | Surgery

Question 28

HPV Vax

Answer 28

Two types Bivalent vax (HPV2) Quadrivalent (HPV4) Given as early as 11 years old

Question 29

Dosing for HPV Vax

Answer 29

3 doses over 6 mo period

Question 30

STDs associated with PID

Answer 30

Chlamydia and gonorrhea

Question 31

Most common pathogens with PID

Answer 31

Gonorrhea and chlamydia

Question 32

Tx for PID

Answer 32

tx of gonorrhea and chlamydia Ceftriaxone plus Doxycycline w or wo metronidazole Azithromycin (doxy if not tolerated) If pen allergy - larger dose Azithromycin

Question 33

PID tx regimens should cover...

Answer 33

``` N.gonorrhea C.trachomatis Anaerobes Gram - Streptococci ```

Question 34

Syphilis transmission routes

Answer 34

Sexual | Vertical

Question 35

Syphilis etiologic agent

Answer 35

Treponema pallidum

Question 36

DOC for syphilis

Answer 36

Benzathine Pen G IM single dose Alternatives: Doxy Tetracycline

Question 37

Tx for trichimonas

Answer 37

Metronidazole | Tinidazole