Statins Flashcards
HMG CO-A reductase inhibitors
lower LDL and increase HDL
decreases CRP levels
-Lab: baseline liver tests
- Baseline for muscle pain
side effect: fatigue and muscle pain
-Rabdo
-drug induced hepatitis
Increasing muscle pain and dark urine with fatigue, what do you order?
CK level for rhabdo
CK will be 5x normal limit–> rhabdo–> lead to acute renal failure
Pt on a statin and has abd pain and jaundice? what do you check?
LFT for drug-induced hepatitis
When do you prescribe fenofibrate?
Fibrate–>Fenofibrate (tricor)
decrease trig and increase HDL
*not good on LDL
Need to use this above 500 trig –> acute pancreatitis
Niacin
how does it work?
Side effect?
Niacin
decrease trig and increase HDL
* does not impact LDL
side effect: facial flushing 30-60 mins after taking it
aspirin taken at the same time can help
Do not take this medication with warm liquids
Bile Acid Sequestrants
Lower LDL levels
helps removed bile
cholestryamine (Prevailte), Cloestipol (colestide)
edu: powder needs to be taken 1 hr before other meds
Lots of GI side effects: nausea and constipation
A patient has an LDL level of 205 mg/dL and the nurse practitioner is wanting to start medication. Which of the following is an appropriate cholesterol-lowering medication for this patient?
A. Lipitor
B. Tricor
C. Colestid
D. Zocor (simvastin)
For patients with an LDL level >190 mg/dL, high-intensity statins are recommended as first line treatment for decreasing LDL levels. Atorvastatin (Lipitor) and Rosuvastatin (Crestor) are examples of high intensity statins.
Simvastatin (Zocor) is a moderate-intensity statin, fenofibrate (Tricor) is best at lowering triglycerides, and bile acid sequestrants like Colestipol (Colestid) have many GI side effects, which make them not a first-line treatment option.
What do we use for DVT treatment?
PE can happen in 45 % of DVT’s
Treatment for 6m after diagnosis
Eliquis
xarelto
warfain
pradaxa
(does not dis
