Diuretics

Question 1

Thiazides
name some-

Uses:
Meds do not combine:
Med Allergy contraindications:
Adverse effects:

Answer 1

HTC, chlorthalidone (longer acting and cardioprotective), indapamide (lozol)

used for: HTN, HF, Edema, DI, HTN with osteoporosis ( reduce ca excretion and stimulates osteoblasts to build bones)

Meds do not combine: lithium (K decrease, increases lithium)

Med Allergy contraindications: sulfa

do not give if GFR is less than 30

Adverse effects: hyperglycemia in DM, elevated LDL and CHOL, precipitate gout, hypo k

Question 2

Potassium Sparing Diuretics

Types:
Amiloride (Midamor)
Triamterene (Dyrenium)
uses:

Mineralocorticoid Receptor Antagonist (Aldactone and Inspra)

Answer 2

HTN with sulfa allergies

watch in out: renal impaired/DM (increase K)

Spironolactone (Aldactone)
Eplernone (Inspra)
used for: HTN, HF, hirsutism

Risks: gynecomastia (increased breast), also risk for benign and malignant tumors.

Question 3

Loop Diuretics

types:
uses:
contraindicated:
AE:
what causes ototoxicity

Answer 3

uses: HF, cirrhosis, CKD, HTN

LaSIX (lasts 6hrs in your pts system)

mech: loop of henle more potent than HCT

types: lasix, bumetanide (bumex)

contri: sulfa allergies

best for HF pts (monitor wt at home)

AE: hypo k, mag, na, cl, pancreatitis, jaudince, and rash,

ototoxicity: if large doses of lasix are administered too quickly.