SNRIs Flashcards
1
Q
Serotonin-norepinephrine reuptake inhibitors
A
1 st line treatments or 2nd line
duloxetine- Cymbalta- neuropathic pain
venlafaxine- effexor
- do not give to HTN pt and s/s: sex dysfunction
2
Q
TCA’s
side effects?
what do we want to assess prior to starting?
A
triptyline
3rd line treatment
increase nor ep and serotonin and blocking acth in the brain
- cheaper
side effects: wt gain, anticholinergic effects (not good for elderly)
get a baseline ECG prior it can
watch for slowing cardiac conduction
worry about OD do not give if suicide risk is high
3
Q
MAOI’s
what do you not eat?
can you use it with other SSRI or st johns?
A
3rd line treatment
examples: Azilect rasagiline, selegiline (elderpryl)
they inhibit monoaoxidase which usually uptakes serotonin
yogurt, cured meats, aged cheese –> HTN
grapefruit juice
St john and SSRI or SNRI will increase the chance of serotonin syndrome.
