Staphylococcus

Question 1

Oxygen Metabolism for Staphylococcus?

Answer 1

Anaerobic

Question 2

Flora

Answer 2

Resident; on skin and mucous membranes

Question 3

Virulence Factors

Answer 3

Protein A: binds to Fc portion on IgG

Hemolysins: lyse RBC’s

Proteases/Hyaluronidase: destroy CT

Lipases/Alpha toxins: damage membranes

Leukocidin: necrotizing fasciitis and pneumonia (canids), exfoliating toxins, biofilm formation

Question 4

Virulence Factor: Protein A

Answer 4

Binds Fc portion of IgG

Question 5

Virulence Factor: Hemolysins

Answer 5

Lyse RBC’s

Question 6

Virulence Factors: Proteases/hyaluronidase

Answer 6

Destroy Connective Tissue

Question 7

Virulence Factors: Lipases/ Alpha Toxins

Answer 7

Damage cell membranes

Question 8

Virulence Factors: Leukocidin

Answer 8

Role in necrotizing fasciitis and pneumonia (in canids, exfoliative toxins, biofilm formation

Question 9

Toxin mediated Diseases?

Answer 9

SUPER ANTIGENS: toxic shock syndrome (humans), Enterotoxin (food poisioning), scaled skin syndrome

Question 10

Suppurations Infections

Answer 10

Skin/soft tissue, systemic, foreign body

- PYODERMA and MASTITIS

Question 11

TREATMENTS: what is the best treatment for FIRST generation infection?

Answer 11

Cephalosporins (Cephalexin)

Question 12

TX: Should Quinolones be used for treatment?

Answer 12

Not the best form; some reported cases of RESISTANCE

Question 13

What is Staphylococcus resistance to?

Answer 13

Clindamycin

Question 14

S. Aureus in humans causes what?

Answer 14

Ulcerative Poyodermatitis - most common NOSOCOMIAL (hospital) pathogen in humans

Question 15

S. aureus - Cattle (what is the disease)

Answer 15

Mastitis - follow hygiene protocols, clean milk equipment, treat with antimicrobials

Question 16

S. aureus - AVIAN (disease)

Answer 16

BUMBLEFOOT

Question 17

S. Pseudintermedius - What species does it target?

Answer 17

CANINE - most common canine isolate

Question 18

S. Pseudintermedius - where typically seen?

Answer 18

In wound infections, surgical site infection, UTI, endocarditis, Necrotixing fasciitis/necrotizing pneumonia, bacterial folliculitis and furunculosis

Question 19

S. hyicus - what species does it infect? Disease associated?

Answer 19

Swine (typically piglets 1-6 wk old), Greasy Pig Disease (exudative epidermitis)

Question 20

MRSA and MRSP are rapidly emerging? T/F

Answer 20

TRUE

Question 21

Staphylococcus, Streptococcus, and Enterococcus are all considered what type of bacteria?

Answer 21

GRAM POSITIVE COCCI