Stages Of HIV (Clinical Manifestations)

Question 1

Primary/ Acute

Stage 0

Answer 1

People who are HIV + may test negative on antibody tests

• why? Because they haven’t developed antibodies yet*

That are still infectious and can transmit HIV

Question 2

Seroconversion

A.K.A Window Period

Answer 2

the process of 1st testing negative and then testing positive

Question 3

Primary/ Acute

Stage 1

Answer 3

2-4 weeks from infection

Antibodies can be detected

Experience flu like symptoms and neurological complications

High Viral Load

Most infectious during this Acute Phase due to High Viral load

CD4 drops TEMPORARILY then goes back up to baseline

Question 4

Why does CD4 temporarily drop before returning back to baseline in Stage 1?

Answer 4

They initially drop be and the body is not use to pumping out more CD4 cells

You are getting hit with the virus for the first time and the body has not had the time to respond to the # of virus in your blood.

Question 5

Chronic

Stage 2

Answer 5

Viral load “stabilizes” after initial immune response

Viral Set Point- amount of virus in body after initial immune response subsides

First several year after becoming infected patients are typically asymptomatic

Question 6

Viral Set Point

Answer 6

amount of virus in body after initial immune response subsides

Question 7

Symptomatic Infection

stage 3

Answer 7

Viral Load ⬆️ CD4 ⬇️

Patients become symptomatic

• fever
• frequent night sweats
• chronic diarrhea
• sever fatigue

Thrush is Associated with this phase

Question 8

How many years from HIV infection ➡️ AIDS ?

Answer 8

10-15 years

IF LEFT UNTREATED